Democratizing nucleic acid-based molecular diagnostic tests for infectious diseases at resource-limited settings–from point of care to extreme point of care

S Chakraborty - Sensors & Diagnostics, 2024 - pubs.rsc.org
The recurring instances of infectious disease outbreaks, coupled with complications such as
comorbidity challenges and antibiotic resistance, consistently underscore the limitations …

Assessment of eight nucleic acid amplification technologies for potential use to detect infectious agents in low-resource settings

JL Cantera, H White, MH Diaz, SG Beall, JM Winchell… - PLoS …, 2019 - journals.plos.org
Nucleic acid amplification technologies (NAATs) are high-performance tools for rapidly and
accurately detecting infectious agents. They are widely used in high-income countries to …

Ensuring accuracy in the development and application of nucleic acid amplification tests (NAATs) for infectious disease

JF Huggett, DM O'Sullivan, S Cowen… - Molecular Aspects of …, 2024 - Elsevier
Diagnostic tests were heralded as crucial during the Coronavirus disease (COVID-19)
pandemic with most of the key methods using bioanalytical approaches that detected larger …

Nucleic Acid Amplification‐Based Technologies (NAAT)—Toward Accessible, Autonomous, and Mobile Diagnostics

V Narasimhan, H Kim, SH Lee, H Kang… - Advanced Materials …, 2023 - Wiley Online Library
The ongoing pandemic and increasing frequency of infectious disease outbreaks due to
climate change, urbanization, and global human migration have put great focus on nucleic …

Portable devices and mobile instruments for infectious diseases point-of-care testing

L Bissonnette, MG Bergeron - Expert review of molecular …, 2017 - Taylor & Francis
Introduction: Rapidity, simplicity, and portability are highly desirable characteristics of tests
and devices designed for performing diagnostics at the point of care (POC), either near …

Current state of commercial point-of-care nucleic acid tests for infectious diseases

JY Zhang, AT Bender, DS Boyle, PK Drain, JD Posner - Analyst, 2021 - pubs.rsc.org
The COVID-19 pandemic has put the spotlight on the urgent need for integrated nucleic acid
tests (NATs) for infectious diseases, especially those that can be used near patient (“point-of …

Emerging technologies in point-of-care molecular diagnostics for resource-limited settings

RW Peeling, R McNerney - Expert review of molecular diagnostics, 2014 - Taylor & Francis
Emerging molecular technologies to diagnose infectious diseases at the point at which care
is delivered have the potential to save many lives in developing countries where access to …

Advances in Point-of-Care Diagnostics for Infectious Disease

ME Natoli, RA Schwarz, M Bond, CE Majors… - Frugal Innovation in …, 2018 - Springer
Recent advances in bioengineering have enabled development of sensitive and specific
diagnostic tests that detect and quantify cells, proteins, and nucleic acids. However, the …

New nucleic acid testing devices to diagnose infectious diseases in resource-limited settings

P Maffert, S Reverchon, W Nasser, C Rozand… - European Journal of …, 2017 - Springer
Point-of-care diagnosis based on nucleic acid testing aims to incorporate all the analytical
steps, from sample preparation to nucleic acid amplification and detection, in a single …

[HTML][HTML] Point-of-need molecular processing of biosamples using portable instrumentation to reduce turnaround time

ME Kambouris, S Siamoglou, Z Kordou, A Milioni… - Biosafety and …, 2020 - Elsevier
Infectious agents, both standard and emerging or engineered, might initiate outbreaks with
global impact and/or existential-level threat potential. Such agents might infect human …