Update οn the diagnosis and management of systemic lupus erythematosus

A Fanouriakis, N Tziolos, G Bertsias… - Annals of the rheumatic …, 2021 - ard.bmj.com
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

Diagnostic criteria for systemic lupus erythematosus: has the time come?

GK Bertsias, C Pamfil, A Fanouriakis… - Nature Reviews …, 2013 - nature.com
Systemic lupus erythematosus (SLE) is a multiorgan disease with protean manifestations.
Because SLE is uncommon and heterogeneous, its diagnosis can pose a considerable …

Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade

GK Bertsias, JE Salmon, DT Boumpas - Annals of the rheumatic …, 2010 - ard.bmj.com
Immune responses against endogenous nuclear antigens are characteristic of systemic
lupus erythematosus (SLE), a highly pleiomorphic disease predominantly affecting young …

Lupus erythematosus 2020

J Narvaez - Medicina Clínica (English Edition), 2020 - Elsevier
Systemic lupus erythematosus (SLE) is a complex autoimmune multisystemic disease of
great clinical heterogeneity and significant potential morbidity and mortality. Although the …

New therapeutic strategies in systemic lupus erythematosus management

M Gatto, M Zen, L Iaccarino, A Doria - Nature Reviews Rheumatology, 2019 - nature.com
The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the
recommendations by international medical associations including EULAR and the ACR, is …

Classifying and diagnosing systemic lupus erythematosus in the 21st century

M Aringer, SR Johnson - Rheumatology, 2020 - academic.oup.com
The EULAR/ACR 2019 classification criteria for SLE constitute a current and optimized
clinical approach to SLE classification. Classification is still not based on molecular …

Systemic lupus erythematosus: a review of the disease and treatment options

S Gurevitz, J Snyder, E Wessel, J Frey… - The Consultant …, 2013 - ingentaconnect.com
OBJECTIVE: To provide an up-to-date review of the etiology, epidemiology, clinical features,
diagnostic findings, and treatment options for systemic lupus erythematosus (SLE). DATA …

[HTML][HTML] Unmet medical needs in systemic lupus erythematosus

A Lateef, M Petri - Arthritis research & therapy, 2012 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune disease of diverse manifestations,
with onset usually in young women in the third to fourth decade of life. The chronic nature of …

How do patients with newly diagnosed systemic lupus erythematosus present? A multicenter cohort of early systemic lupus erythematosus to inform the development …

M Mosca, KH Costenbader, SR Johnson… - Arthritis & …, 2019 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE) presents with nonspecific signs and
symptoms that are also found in other conditions. This study aimed to evaluate …

[HTML][HTML] Systemic lupus erythematosus: new diagnostic and therapeutic approaches

S Lazar, JM Kahlenberg - Annual review of medicine, 2023 - annualreviews.org
Systemic lupus erythematosus (SLE) is a devastating autoimmune disease that can result in
substantial morbidity and mortality. Diagnosis and treatment of SLE are clinical challenges …