Associations among vascular risk factors, neuroimaging biomarkers, and cognition: preliminary analyses from the Multi‐Ethnic Study of Atherosclerosis (MESA)
SN Lockhart, CL Schaich, S Craft… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Little is known about how antecedent vascular risk factor (VRF) profiles impact
late‐life brain health. Methods We examined baseline VRFs, and cognitive testing and …
late‐life brain health. Methods We examined baseline VRFs, and cognitive testing and …
[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
Vascular cognitive impairment and dementia: An early career researcher perspective
The field of vascular contributions to cognitive impairment and dementia (VCID) is evolving
rapidly. Research in VCID encompasses topics aiming to understand, prevent, and treat the …
rapidly. Research in VCID encompasses topics aiming to understand, prevent, and treat the …
Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease
J Li, YJ Wang, M Zhang, ZQ Xu, CY Gao, CQ Fang… - Neurology, 2011 - AAN Enterprises
Objective: Growing evidence suggests that vascular risk factors (VRF) contribute to cognitive
decline. The aim of this study was to investigate the impact of VRF on the conversion from …
decline. The aim of this study was to investigate the impact of VRF on the conversion from …
Vascular cognitive impairment: a preventable component of dementia
MR Azarpazhooh, V Hachinski - Handbook of Clinical Neurology, 2019 - Elsevier
For many decades during the 20th century, the common belief was that the slow
strangulation of the brains' blood supply from hardening of the brain arteries led to chronic …
strangulation of the brains' blood supply from hardening of the brain arteries led to chronic …
Past antihypertensive medication use is associated with lower levels of small vessel disease and lower Aβ plaque stage in the brains of older individuals
AJ Affleck, PS Sachdev… - … and Applied Neurobiology, 2023 - Wiley Online Library
Aims This study assesses the association of antihypertensive medication use on the
severities of neuropathological cerebrovascular disease (CVD excluding lobar infarction) in …
severities of neuropathological cerebrovascular disease (CVD excluding lobar infarction) in …
Cerebral small vessel disease, medial temporal lobe atrophy and cognitive status in patients with ischaemic stroke and transient ischaemic attack
Background and purpose Small vessel disease (SVD) and Alzheimer's disease (AD) are two
common causes of cognitive impairment and dementia, traditionally considered as distinct …
common causes of cognitive impairment and dementia, traditionally considered as distinct …
[HTML][HTML] Causes and consequences of cerebral small vessel disease. The RUN DMC study: a prospective cohort study. Study rationale and protocol
AGW van Norden, KF de Laat, RAR Gons… - BMC neurology, 2011 - Springer
Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans
of elderly people and is related to vascular risk factors and cognitive and motor impairment …
of elderly people and is related to vascular risk factors and cognitive and motor impairment …
[HTML][HTML] Regional White Matter Hyperintensities and Alzheimer's Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment
P Newton, J Tchounguen, C Pettigrew… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …
Recent studies suggest there may be a mechanistic link between AD and small vessel …
[HTML][HTML] METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for …
M Dichgans, J Wardlaw, E Smith, V Zietemann… - Alzheimer's & …, 2016 - Elsevier
Dementia is a global problem and major target for health care providers. Although up to 45%
of cases are primarily or partly due to cerebrovascular disease, little is known of these …
of cases are primarily or partly due to cerebrovascular disease, little is known of these …