Capecitabine loaded potato starch-chitosan nanoparticles: A novel approach for targeted therapy and improved outcomes in aggressive colon cancer

S Bhattacharya, A Page, P Shinde - European Journal of Pharmaceutics …, 2024 - Elsevier
Aggressive colon cancer treatment poses significant challenges. This study investigates the
potential of innovative carbohydrate-based nanoparticles for targeted Capecitabine (CTB) …

[PDF][PDF] Capecitabine loaded polymeric nanoparticles for colorectal cancer targeting

L Padhy, CN Patra, GK Jena - World J …, 2018 - wjpr.s3.ap-south-1.amazonaws.com
Colorectal cancer is cancer that starts in colon and rectum. As the colon and rectum are the
most interior part of gastrointestinal tract, it is a great challenge to target drug to colon and …

Combination chemotherapy against colorectal cancer cells: Co-delivery of capecitabine and pioglitazone hydrochloride by polycaprolactone-polyethylene glycol …

FD Pouya, R Salehi, Y Rasmi, F Kheradmand… - Life Sciences, 2023 - Elsevier
Background Colorectal cancer causes numerous deaths despite many treatment options.
Capecitabine (CAP) is the standard chemotherapy regimen for colorectal cancer, and …

An innovative synergistic combination using eudragit-coated galactosylated PLGA-pluronic nanoparticles for addressing colorectal cancer

PR Raikar, PM Dandagi, VM Kumbar - Journal of Drug Delivery Science …, 2024 - Elsevier
The goal of this research was to find a way to enhance the pharmacological activity of
Capecitabine (CAP) and Thymoquinone (TQ) while also decreasing the likelihood of drug …

Paclitaxel loaded EDC-crosslinked fibroin nanoparticles: a potential approach for colon cancer treatment

DT Pham, N Saelim, W Tiyaboonchai - Drug delivery and translational …, 2020 - Springer
Colon cancer is one of the most life-threatening cancers with high incidence and mortality
rates. Current first-line treatments are ineffective and possess many unwanted effects. The …

Physicochemical characterization, in vitro and in vivo evaluation of chitosan/carrageenan encumbered with Imatinib mesylate-polysarcosine nanoparticles for …

S Bhattacharya, S Bonde, K Hatware, S Sharma… - International Journal of …, 2023 - Elsevier
The objective of this investigation was to fabricate nanoparticles consisting of Imatinib
mesylate-poly sarcosine-loaded chitosan/carrageenan in order to attain prolonged drug …

N-trimethyl chitosan coated nano-complexes enhance the oral bioavailability and chemotherapeutic effects of gemcitabine

G Chen, D Svirskis, W Lu, M Ying, H Li, M Liu… - Carbohydrate …, 2021 - Elsevier
N-trimethyl chitosan (TMC) is a multifunctional polymer that can be used in various
nanoparticle forms in the pharmaceutical, nutraceutical and biomedical fields. In this study …

The Advances in Chitosan-based Drug Delivery Systems for Colorectal Cancer: A Narrative Review

DS Ali, HO Othman, ET Anwer - Current Pharmaceutical …, 2023 - ingentaconnect.com
Colorectal cancer (CRC) is considered a lethal cancer all around the world, and its
incidence has been reported to be increasing. Chemotherapeutic drugs commonly used for …

Vascular targeted chitosan-derived nanoparticles as docetaxel carriers for gastric cancer therapy

E Zhang, R Xing, S Liu, K Li, Y Qin, H Yu, P Li - International journal of …, 2019 - Elsevier
A gastric cancer angiogenesis marker peptide, GX1, is promising to be a desirable ligand for
anti-angiogenesis targeted drug of gastric cancer treatment. In this study, GX1 was utilized to …

Formulation and characterization of gallic acid and quercetin chitosan nanoparticles for sustained release in treating colorectal cancer

P Patil, S Killedar - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
Cancer was ranked as the second leading cause of death, and colon cancer is recognized
as third most common cancer worldwide with high morbidity and mortality …