Oral colon cancer targeting by chitosan nanocomposites

A Bose, TW Wong - Applications of Nanocomposite Materials in Drug …, 2018 - Elsevier
Chitosan is a deacetylated derivative of chitin. It receives a widespread application in drug
delivery system design due to its biodegradability, biocompatibility, and availability of …

[PDF][PDF] Design and characterization of Gaur gum coated chitosan nanoparticles for delivery of 5-Fluorouracil for effective treatment of colon cancer

S Garg, A Shukla, A Garg - Journal of Medical Pharmaceutical and …, 2015 - jmpas.com
The present study was aimed to develop gaur gum (GG) coated chitosan nanoparticles as
vector to provide successful delivery of 5-fluorouracil (5-FU). Guar gum anchored chitosan …

[PDF][PDF] Curcumin loaded eudragit s100/plga nanoparticles in treatment of colon cancer: Formulation, optimization, and in-vitro cytotoxicity study

A Saraf, N Dubey, N Dubey… - Indian J. Pharm. Educ …, 2021 - pdfs.semanticscholar.org
Introduction: Polymeric nanoparticles provide a promising strategy for site-specific delivery
of dietary phytochemicals in the treatment of colon cancer. Curcumin (CU) is a dietary …

Docetaxel loaded chitosan nanoparticles: formulation, characterization and cytotoxicity studies

A Jain, K Thakur, P Kush, UK Jain - International journal of biological …, 2014 - Elsevier
The primary objective of the present investigation was to explore biodegradable chitosan as
a polymeric material for formulating docetaxel nanoparticles (DTX-NPs) to be used as a …

CD44 targeted delivery of hyaluronic acid-coated polymeric nanoparticles against colorectal cancer

N Phatak, S Bhattacharya, D Shah, L Manthalkar… - …, 2023 - Taylor & Francis
Aim: To develop hyaluronic acid (HA)-coated poly-lactic-co-glycolic acid (PLGA)-
polysarcosine (PSAR) coupled sorafenib tosylate (SF) polymeric nanoparticles for targeted …

REVOLUTIONIZING CANCER TREATMENT: THE ROLE OF CHITOSAN NANOPARTICLES IN THERAPEUTIC ADVANCEMENTS

AK Lunawat, S Thakur, BD Kurmi, GD Gupta… - Journal of Drug Delivery …, 2024 - Elsevier
Cancer poses a significant global health threat, with millions of new cases and deaths
annually reported. The traditional chemotherapy faces challenges due to poor drug …

Effective tumor-targeted delivery of etoposide using chitosan nanoparticles conjugated with folic acid and sulfobetaine methacrylate

S Hua, J Yu, J Shang, H Zhang, J Du, Y Zhang… - RSC …, 2016 - pubs.rsc.org
We demonstrated chitosan (CS)-based biocompatible nanoparticles coated with folic acid
(FA) and poly (sulfobetaine methacrylate)(PSBMA) as an effective tumor-specific drug …

Enhanced anti-proliferative effect of carboplatin in ovarian cancer cells exploiting chitosan-poly (lactic glycolic acid) nanoparticles

FR Alassaif, ER Alassaif, AK Kaushik… - Recent Patents on …, 2023 - ingentaconnect.com
Objective: The present article aimed to enhance the therapeutic efficacy of carboplatin (CP)
using the formulation of chitosan-poly (lactic glycolic acid) nanoparticles (CS-PLGA NPs) …

[HTML][HTML] Nanoformulation of Paclitaxel: Exploring the Cyclodextrin/PLGA Nano Delivery Carrier to Slow Down Paclitaxel Release, Enhance Accumulation in Vivo

P Ma, JY Huang, J Liu, Y Zhu, J Chen, J Chen… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Improving the aggregation and penetration in tumor sites increases the anti-
tumor efficacy of nanomedicine. In the current study, we designed cyclodextrin modified …

Cutting-edge tumor nanotherapy: Advancements in 5-fluorouracil Drug-loaded chitosan nanoparticles

MH Karami, M Abdouss - Inorganic Chemistry Communications, 2024 - Elsevier
Currently, cancer continues to be a significant contributor to global mortality rates. Scientists
and researchers are actively working to find efficient approaches for cancer treatment that …