Isolation and identification of age-related DNA methylation markers for forensic age-prediction

SH Yi, LC Xu, K Mei, RZ Yang, DX Huang - Forensic Science International …, 2014 - Elsevier
Age-prediction is an important part of forensic science. There is no available method of
individual age-prediction for general forensic biological samples at crime scenes …

Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation

I Smeers, R Decorte, W Van de Voorde… - Forensic Science …, 2018 - Elsevier
DNA methylation is a promising biomarker for forensic age prediction. A challenge that has
emerged in recent studies is the fact that prediction errors become larger with increasing …

[Retracted] DNA Methylation Biomarkers‐Based Human Age Prediction Using Machine Learning

A Zaguia, D Pandey, S Painuly, SK Pal… - Computational …, 2022 - Wiley Online Library
Purpose. Age can be an important clue in uncovering the identity of persons that left
biological evidence at crime scenes. With the availability of DNA methylation data, several …

Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications

J Naue - Genes & Genomics, 2023 - Springer
Background DNA analysis for forensic investigations has a long tradition with important
developments and optimizations since its first application. Traditionally, short tandem …

A novel strategy for forensic age prediction by DNA methylation and support vector regression model

C Xu, H Qu, G Wang, B Xie, Y Shi, Y Yang, Z Zhao… - Scientific reports, 2015 - nature.com
High deviations resulting from prediction model, gender and population difference have
limited age estimation application of DNA methylation markers. Here we identified 2,957 …

Epigenetic clocks may come out of rhythm—implications for the estimation of chronological age in forensic casework

BE Koop, A Reckert, J Becker, Y Han… - International Journal of …, 2020 - Springer
There is a growing perception that DNA methylation may be influenced by exogenous and
endogenous parameters. Knowledge of these factors is of great relevance for the …

Inter-laboratory adaption of age estimation models by DNA methylation analysis—problems and solutions

M Pfeifer, T Bajanowski, J Helmus… - International Journal of …, 2020 - Springer
In recent years, a lot of age prediction models based on different CpG motives in different
cell types were published determining the biological age of a person by DNA methylation …

Age estimation using DNA methylation technique in forensics: a systematic review

C Maulani, EI Auerkari - Egyptian Journal of Forensic Sciences, 2020 - Springer
Background In addition to the DNA sequence, epigenetic markers have become substantial
forensic tools during the last decade. Estimating the age of an individual from human …

[HTML][HTML] DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

L Manco, HC Dias - Forensic Science International, 2022 - Elsevier
DNA methylation (DNAm) evaluation has been investigated in various tissues and body
fluids allowing the identification of many CpG markers with high correlations with …

An ELOVL2-based epigenetic clock for forensic age prediction: a systematic review

E Paparazzo, V Lagani, S Geracitano… - International Journal of …, 2023 - mdpi.com
The prediction of chronological age from methylation-based biomarkers represents one of
the most promising applications in the field of forensic sciences. Age-prediction models …