Abstract Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the
detoxification of alcohol-derived acetaldehyde and endogenous aldehydes. The inactivating …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a non-cytochrome P450 mitochondrial
aldehyde oxidizing enzyme. It is best known for its role in the metabolism of acetaldehyde, a …

Alcoholic cardiomyopathy is manifested as cardiac hypertrophy, disrupted contractile
function and myofibrillary architecture. An ample amount of clinical and experimental …

ABSTRACT Introduction: Aldehyde dehydrogenase-2 (ALDH2) is a main contributor of the
alcohol elimination process. Functional polymorphism in the ALDH2 gene and its inactive …

Background and Aims Emerging evidences have shown that the Glu504Lys variant in
ALDH2 gene may greatly reduce the ability of ALDH2 to metabolize acetaldehyde, which …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a key mitochondrial enzyme in the
metabolism of aldehydes and may have beneficial cardiovascular effects for conditions such …

Alcohol consumption is a serious health issue in Korea in terms of the amount consumed
and the behavior related to its consumption. Aldehyde dehydrogenase 2 (ALDH2) is a key …

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are the major
enzymes responsible for alcohol metabolism in humans. Emerging evidences have shown …

Asian Americans are one of the fastest-growing populations in the United States. A relatively
large subset of this population carries a unique loss-of-function point mutation in aldehyde …

Background—Coronary spastic angina (CSA) is a common disease among East Asians,
including Japanese. The prevalence of alcohol flushing syndrome associated with deficient …