The CEACAM1 expression is decreased in the liver of severely obese patients with or without diabetes

W Lee - Diagnostic pathology, 2011 - Springer
Background Type 2 diabetes is mainly caused by insulin resistance. The carcinoembryonic
antigen-related cell adhesion molecule 1 (CEACAM1) is an important candidate for causing …

Reduced hepatic carcinoembryonic antigen-related cell adhesion molecule 1 level in obesity

G Heinrich, HT Muturi, K Rezaei, QY Al-Share… - Frontiers in …, 2017 - frontiersin.org
Impairment of insulin clearance is being increasingly recognized as a critical step in the
development of insulin resistance and metabolic disease. The carcinoembryonic antigen …

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice

L Russo, HT Muturi, HE Ghadieh, SS Ghanem… - Diabetologia, 2017 - Springer
Aims/hypothesis The carcinoembryonic antigen-related cell adhesion molecule 1
(CEACAM1) promotes insulin clearance. Mice with global null mutation (Cc1−/−) or with liver …

Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice

G Heinrich, S Ghosh, AM DeAngelis… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: The carcinoembryonic antigen-related cell adhesion molecule 1
(CEACAM1) is a transmembrane glycoprotein with pleotropic functions, including clearance …

Forced hepatic overexpression of CEACAM1 curtails diet-induced insulin resistance

QY Al-Share, AM DeAngelis, SG Lester, TA Bowman… - Diabetes, 2015 - Am Diabetes Assoc
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin
sensitivity by promoting hepatic insulin clearance. Liver-specific inactivation or global null …

CEACAM1, a novel serum biomarker for pancreatic cancer

DM Simeone, B Ji, M Banerjee, T Arumugam, D Li… - Pancreas, 2007 - journals.lww.com
Objectives: Serum biomarkers for early diagnosis of pancreatic adenocarcinoma are not
currently available. We recently observed elevated expression of CEACAM1 in pancreatic …

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism

AM DeAngelis, G Heinrich, T Dai, TA Bowman… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Liver-specific inactivation of carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) by a dominant-negative transgene (l-SACC1 mice) impaired insulin …

Assay of serum CEACAM1 as a potential biomarker for breast cancer

C Yang, P He, Y Liu, Y He, C Yang, Y Du, M Zhou… - Clinica Chimica …, 2015 - Elsevier
Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a
widely expressed multi-functional adhesion molecule reported to serve as a serum …

Loss of carcinoembryonic antigen‐related cell adhesion molecule 1 expression is an adverse prognostic factor in hepatocellular carcinoma

PV Cruz, T Wakai, Y Shirai, N Yokoyama… - … Journal of the …, 2005 - Wiley Online Library
BACKGROUND Carcinoembryonic antigen‐related cell adhesion molecule 1 (CEACAM1) is
a negative regulator of tumor cell growth, and may function as a tumor suppressor …

The different expression of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) and possible roles in gastric carcinomas

CJ Zhou, B Liu, KX Zhu, QH Zhang, TG Zhang… - … -Research and Practice, 2009 - Elsevier
The purpose of this study was to investigate the expression of carcinoembryonic antigen-
related cell adhesion molecule 1 (CEACAM1) and its effects on promoting angiogenesis in …