Defenses against Oxidative Stress in Neisseria gonorrhoeae: a System Tailored for a Challenging Environment

KL Seib, HJ Wu, SP Kidd, MA Apicella… - Microbiology and …, 2006 - Am Soc Microbiol
Neisseria gonorrhoeae is a host-adapted pathogen that colonizes primarily the human
genitourinary tract. This bacterium encounters reactive oxygen and reactive nitrogen species …

Neisseria gonorrhoeae physiology and pathogenesis

LR Green, J Cole, EFD Parga, JG Shaw - Advances in microbial physiology, 2022 - Elsevier
Neisseria gonorrhoeae is an obligate human pathogen that is the cause of the sexually
transmitted disease gonorrhoea. Recently, there has been a surge in gonorrhoea cases that …

The gonococcal transcriptome during infection of the lower genital tract in women

R McClure, K Nudel, P Massari, B Tjaden, X Su… - PloS one, 2015 - journals.plos.org
Gonorrhea is a highly prevalent disease resulting in significant morbidity worldwide, with an
estimated 106 cases reported annually. Neisseria gonorrhoeae, the causative agent of …

Dinner date: Neisseria gonorrhoeae central carbon metabolism and pathogenesis

AD Potter, AK Criss - Emerging Topics in Life Sciences, 2023 - portlandpress.com
Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea,
is a human-adapted pathogen that does not productively infect other organisms. The …

Transcript analysis of nrrF, a Fur repressed sRNA of Neisseria gonorrhoeae

TF Ducey, L Jackson, J Orvis, DW Dyer - Microbial pathogenesis, 2009 - Elsevier
Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to
iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling …

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae

KC Ma, TD Mortimer, AL Hicks, NE Wheeler… - Nature …, 2020 - nature.com
Neisseria gonorrhoeae is an urgent public health threat due to rapidly increasing incidence
and antibiotic resistance. In contrast with the trend of increasing resistance, clinical isolates …

Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages

SM Zughaier, JL Kandler, WM Shafer - PloS one, 2014 - journals.plos.org
Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted
infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly …

Identification of sRNAs expressed by the human pathogen Neisseria gonorrhoeae under disparate growth conditions

R McClure, B Tjaden, C Genco - Frontiers in microbiology, 2014 - frontiersin.org
In the last several years, bacterial gene regulation via small RNAs (sRNAs) has been
recognized as an important mechanism controlling expression of essential proteins that are …

Neisseria gonorrhoeae Exposed to Sublethal Levels of Hydrogen Peroxide Mounts a Complex Transcriptional Response

SJ Quillin, AJ Hockenberry, MC Jewett, HS Seifert - Msystems, 2018 - Am Soc Microbiol
Neisseria gonorrhoeae mounts a substantial transcriptional program in response to
hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during …

The Composition and Metabolic Phenotype of Neisseria gonorrhoeae Biofilms

ML Falsetta, CT Steichen, AG McEwan, C Cho… - Frontiers in …, 2011 - frontiersin.org
Neisseria gonorrhoeae has been shown to form biofilms during cervical infection. Thus,
biofilm formation may play an important role in the infection of women. The ability of N …