Herpes simplex encephalitis (HSE) remains one of the most devastating infections of the
central nervous system despite available antiviral therapy. Children and adolescents …

Herpes simplex encephalitis (HSE) remains one of the most devastating infections of the
central nervous system despite available antiviral therapy. Children and adolescents …

OBJECTIVE. The purpose of this study was to review the experience with herpes simplex
encephalitis at the Hospital for Sick Children over the past 12 years. METHODS. All patients …

Herpes simplex virus is the most common cause of sporadic (nonepidemic), fatal viral
encephalitis. The clinical suspicion usually requires biopsy for differential diagnosis …

Dramatic progress has been made recently in diagnosing and treating herpes simplex virus
encephalitis (HSVE). Advances in imaging technology have greatly enhanced our ability to …

Knowledge on pediatric herpes simplex virus encephalitis is limited. Here we summarize 6
neonates and 32 children diagnosed by polymerase chain reaction (n= 37) or serological …

Herpes simplex virus infections of the central nervous system remain a significant cause of
morbidity and mortality, in spite of safe and efficacious antiviral therapy. Advances in the …

The prognosis of herpes simplex encephalitis (HSE) depends on the early and appropriate
administration of specific antiviral therapy. We retrospectively reviewed 38 cases of children …

Neonatal herpes simplex virus infections are a common problem in the United States,
occurring at an incidence of one in approximately 3,500 deliveries. In the absence of …

Clinical and basic science research carried out in recent years into herpes simplex
encephalitis (HSE) have shown that the concept of a “classical” picture of HSE in children is …