Interferon-alpha therapy in chronic myeloid leukemia

D Lutz - Wiener Medizinische Wochenschrift (1946), 1993 - europepmc.org
In 1983 was for the first time reported that natural interferon-alpha (IFN-alpha) has a
cytoreductive effect when used for treatment of chronic myelogenic leukemia (CML). The …

Evolving modalities of treatment with interferon alfa-2b for Ph1-positive chronic myelogenous leukaemia

E Morra, G Alimena, M Lazzarino, AM Liberati… - European Journal of …, 1991 - Elsevier
We have administered interferon alfa-2b, alone or in combination with chemotherapy, to 126
Ph 1-positive chronic myelogenous leukaemia patients. Of 71 early chronic phase (CP) …

Interferon alpha-2b as therapy for Ph'-positive chronic myelogenous leukemia: a study of 82 patients treated with intermittent or daily administration

G Alimena, E Morra, M Lazzarino, AM Liberati… - 1988 - ashpublications.org
The authors treated a total of 82 patients with Ph′-positive chronic myelogenous leukemia
(CML) with recombinant interferon alpha-2b (IFN alpha-2b). Sixty-five patients in chronic …

Hematological and cytogenetic response of interferon alpha 2b alone and combined interferon alpha plus cytarabine as a first-line treatment in chronic myeloid …

E Tothova, M Fricova, A Kafkova, N Stecova… - …, 2000 - pubmed.ncbi.nlm.nih.gov
Treatment with interferon-alpha (IFNalpha) prolongs survival in chronic myeloid leukemia
(CML). Additionally, cytarabine (AraC) can reduce the number of Ph+ metaphases …

Management of chronic myeloid leukemia in chronic phase with autologous stem cell transplantation and alpha-2 interferon: cytogenetic and clinical results

G Alimena, G Meloni, MR De Cuia… - Leukemia & …, 1993 - Taylor & Francis
Forty-eight patients with chronic myeloid leukemia (CML) in chronic phase (CP) were treated
by autologous stem cells transplantation (ASCT) and α Interferon (IFN) with three …

[引用][C] 7 The MD Anderson Cancer Center experience with interferon-α therapy in chronic myelogenous leukaemia

M Talpaz, HM Kantarjian, S O'Brien… - Baillière's clinical …, 1997 - Elsevier
The MD Anderson Cancer Center (MDACC) clinical experience with interferon-c~(IFN-cz)
therapy in chronic myelogenous leukaemia (CML) spans a period of approximately 15 …

Interferon-α Combined with Cytarabine in Chronic Myelogenous Leukemia-Clinical Benefits

M Lindauer, T Fischer - Leukemia & Lymphoma, 2001 - Taylor & Francis
During the last decade, several studies have evaluated the treatment of chronic phase
chronic myeloid leukemia (CML) with a combination of interferon (IFN)-α and low-dose …

Recombinant interferon‐α2A as maintenance treatment for patients with advanced stage chronic lymphocytic leukemia responding to chemotherapy

F Ferrara, V Rametta, G Mele, I Antinolfi… - American journal of …, 1992 - Wiley Online Library
Forty‐five patients suffering from advanced B‐CLL were randomized to receive interferon‐α
(IFNα) or no treatment after achieving complete remission or partial response, following a …

Sequential therapy with recombinant interferons gamma and alpha in patients with unfavorable prognosis of chronic myelocytic leukemia: Clinical responsiveness to …

HH Bartsch, K Pfizenmaier, A Hanusch… - … journal of cancer, 1989 - Wiley Online Library
Natural and recombinant interferons (IFNs) have already demonstrated therapeutic efficacy,
including cytogenetic remissions, in patients with chronic myelocytic leukemia (CML). We …

Response to the combined administration of interferons alpha and gamma after failure of single interferon therapy in chronic myelogenous leukaemia

O Kloke, R Becher, N Niederle - Blut, 1987 - Springer
A previously untreated patient with benign phase chronic myelogenous leukaemia (CML)
was treated with recombinant Interferon alpha-2b. Haematological remission was induced …