Several basic experimental and clinical studies were carried out in an attempt to improve the
efficacy of alpha interferon therapy for chronic myelogenous leukaemia (CML). First, the …

BACKGROUND AND OBJECTIVE: Interferon-a (IFN) is increasingly being used as the drug
of choice in chronic myeloid leukemia patients. The main objectives of the study were to …

The French Chronic Myeloid Leukemia Study Group prospective randomized study results
indicate that the addition of cytarabine to alpha interferon (IFN-α) increases the rate of major …

To improve the management of chronic myeloid leukemia (CML) in a single center, we used
interferon alpha (IFN alpha) to treat newly diagnosed CML patients and investigated the …

BACKGROUND: Standard or conventional treatment of chronic myeloid leukemia (CML) had
little effect on the course and the duration of the disease. Treatment with human natural and …

Chronic myelogenous leukemia Philadelphia chromosome-positive(CML Ph') is
characterized by a multistep evolutionary course starting with a benign phase of variable …

At the present time, the combination of interferon alpha and hydroxyurea represents the
standard treatment of the chronic phase of CML. Using this approach, survival can be …

In a study using human IFN-alpha, 36 of 51 patients with chronic phase CML achieved a
complete hematologic remission. More significantly, 20 patients showed suppression of Ph …

Combination of chemotherapy and interferon alfa-2b in the treatment of chronic
myelogenous leukemia CNRS Inist Pascal-Francis CNRS Pascal and Francis Bibliographic …

Eighteen patients with relapse of chronic myelogenous leukemia (CML) after allogeneic
bone marrow transplantation (BMT) were treated with recombinant human alpha 2a …