Combination therapy with interferon alpha‐2b plus low‐dose interferon gamma in pretreated patients with Ph‐positive chronic myelogenous leukaemia

UB Wandl, O Kloke, M Nagel‐Hiemke… - British journal of …, 1992 - Wiley Online Library
Between March 1988 and July 1990, 28 adults with chronic myelogenous leukaemia (CML)
were treated with a combination of recombinant human interferon (IFN) alpha‐2b sc (initial …

Use of alpha interferon for the treatment of relapse of chronic myelogenous leukemia in chronic phase after allogeneic bone marrow transplantation

CS Higano, WH Raskind, JW Singer - 1992 - ashpublications.org
Eighteen patients with relapse of chronic myelogenous leukemia (CML) after allogeneic
bone marrow transplantation (BMT) were treated with recombinant human alpha 2a …

Interferon alpha‐2b as therapy for patients with Ph '‐positive chronic myelogenous leukemia

G Alimena, E Morra, M Lazzarino… - European Journal of …, 1990 - Wiley Online Library
We treated 114 ph1+ chronic myeloid leukemia (CML) patients, 105 of whom were in
chronic phase (CP) and 9 in accelerated phase (AP), with interferon alpha‐2b (IFN α‐2b) at …

A randomized study comparing interferon (IFNα) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic-phase chronic myeloid leukemia …

T Kühr, S Burgstaller, U Apfelbeck, W Linkesch… - Leukemia Research, 2003 - Elsevier
This multicenter randomized phase III study was designed to compare the efficacy and
toxicity of IFNα-2c (3.5 MU/d) in combination with either araC (10mg/m2 d1-10) or …

[HTML][HTML] The Combination of Interferon-Alpha with Imatinib in Early Chronic Phase Chronic Myeloid Leukemia Patients Induces a Significant Improvement of the …

F Palandri, F Castagnetti, I Iacobucci, M Amabile… - Blood, 2009 - Elsevier
Abstract Abstract 2192 Poster Board II-169 Thanks to its striking effectiveness, imatinib (IM)
is the current standard of therapy in chronic myeloid leukemia (CML). However, Interferon …

[PDF][PDF] Interferon-alpha in chronic myeloid leukemia revisited: A long-term retrospective study in Central and Northern Moravia.

E Faber, A Kuba, J Zapletalova… - … Papers of the …, 2013 - biomed.papers.upol.cz
Aims. We assessed the long-term outcome of consecutive patients in the chronic phase of
chronic myeloid leukemia (CML) treated with interferon-alpha (INF-α) in Central and …

Treatment of Chronic and Acute Phase Chronic Myelogenous Leukemia with Interferon-α2b and, Interferon-γ

N Niederle, O Kloke, R Osieka, D May… - … Leukemia and Interferon …, 1988 - Springer
The interferons (IFN s) are a group of proteins which can exert a wide range of biologie
effects on normal tissue cells, host immune defense cells, and cancer cells [5, 9, 12, 20] …

Multicenter prospective study of interferon-α versus bone marrow transplantation for newly diagnosed patients with chronic myelogenous leukemia: a preliminary …

K Ohnishi, T Ino, Y Kishimoto, N Usui… - Cancer chemotherapy …, 2001 - Springer
Interferon-α (IFN-α) therapy was compared with bone marrow transplantation (BMT) in
patients with chronic myelogenous leukemia (CML) in a multicenter, prospective study. Of …

Combined interferon alfa-2a and cytosine arabinoside as first-line treatment for chronic myeloid leukemia

CK Arthur, DDF Ma - Acta haematologica, 1993 - karger.com
Thirty patients with chronic myeloid leukemia in chronic phase and less than 1 year from
diagnosis were treated with a combination of interferon alfa-2a (IFN) 9 million units daily …

Interferon-α for the treatment of elderly patients with chronic myeloid leukaemia

W Hilbe, U Apfelbeck, M Fridrik, M Bernhart… - Leukemia research, 1998 - Elsevier
The present retrospective analysis is based on data of 213 patients with chronic myeloid
leukaemia (CML). They were treated with interferon (IFN) α-2C (Berofor®) at daily doses of …