[HTML][HTML] Potent natural antioxidant carveol attenuates MCAO-stress induced oxidative, neurodegeneration by regulating the Nrf-2 pathway

I Malik, FA Shah, T Ali, Z Tan, A Alattar… - Frontiers in …, 2020 - frontiersin.org
Ischemic stroke is a severe neurological disorder with a high prevalence rate in developed
countries. It is characterized by permanent or transient cerebral ischemia and it activates …

[HTML][HTML] D-Carvone inhibit cerebral ischemia/reperfusion induced inflammatory response TLR4/NLRP3 signaling pathway

M Dai, L Wu, K Yu, R Xu, Y Wei, A Chinnathambi… - Biomedicine & …, 2020 - Elsevier
To explore the present treatment strategies for ischemic stroke lowered by ischemia-
reperfusion (I/R) injury, to hypothesize the effect of d-Carvone on cerebral I/R brain injury …

Carvacryl acetate, a semisynthetic monoterpenic ester obtained from essential oils, provides neuroprotection against cerebral ischemia reperfusion-induced oxidative …

Y Song, LB Wang, Y Bei, DX Qin, LY Ai, QZ Ma… - Food & function, 2020 - pubs.rsc.org
Carvacryl acetate (CA) is a semisynthetic monoterpenic ester obtained from essential oils,
and it exerts an antioxidation effect. The purpose of our study was to investigate whether CA …

Licochalcone B attenuates neuronal injury through anti-oxidant effect and enhancement of Nrf2 pathway in MCAO rat model of stroke

B Zhou, H Wang, B Zhang, L Zhang - International immunopharmacology, 2021 - Elsevier
Background Investigating anti-oxidant therapies that lead to the diminution of oxidative injury
is priority in clinical. We herein aimed to explore whether and how Licochalcone B (Lico B) …

[Retracted] Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti‐inflammatory Mechanism

AJ Muhammad, L Hao, LT Al Kury… - Oxidative Medicine …, 2022 - Wiley Online Library
Major depressive disorder (MDD) is a progressive deteriorating mental state with a feeling of
worthlessness and frequent mood swings. Several studies reported the favorable effects of …

[HTML][HTML] β-carotene provides neuroprotection after experimental traumatic brain injury via the Nrf2-ARE pathway

P Chen, L Li, Y Gao, Z Xie, Y Zhang, Z Pan… - Journal of Integrative …, 2019 - imrpress.com
We investigate whether β-carotene, a known natural antioxidant, can reduce oxidative stress
induced by traumatic brain injury. In addition, we investigated the underlying mechanism of …

Protocatechualdehyde protects against cerebral ischemia-reperfusion-induced oxidative injury via protein kinase Cε/Nrf2/HO-1 pathway

C Guo, S Wang, J Duan, N Jia, Y Zhu, Y Ding… - Molecular …, 2017 - Springer
Oxidative stress is closely related to the pathogenesis of ischemic stroke.
Protocatechualdehyde (PCA) is a phenolic acid compound that has the putative antioxidant …

Activation of the Nrf2 defense pathway contributes to neuroprotective effects of phloretin on oxidative stress injury after cerebral ischemia/reperfusion in rats

Y Liu, L Zhang, J Liang - Journal of the neurological sciences, 2015 - Elsevier
Oxidative stress is considered a major contributing factor in cerebral ischemia/reperfusion
injury. Phloretin, a dihydrochalcone belonging to the flavonoid family, is particularly rich in …

[HTML][HTML] Rosmarinic acid elicits neuroprotection in ischemic stroke via Nrf2 and heme oxygenase 1 signaling

HY Cui, XJ Zhang, Y Yang, C Zhang… - Neural regeneration …, 2018 - journals.lww.com
Rosmarinic acid (RA) can elicit a neuroprotective effect against ischemic stroke, but the
precise molecular mechanism remains poorly understood. In this study, an experimental …

Carvacrol Exerts Neuroprotective Effects Via Suppression of the Inflammatory Response in Middle Cerebral Artery Occlusion Rats

Z Li, C Hua, X Pan, X Fu, W Wu - Inflammation, 2016 - Springer
Increasing evidence demonstrates that inflammation plays an important role in cerebral
ischemia. Carvacrol, a monoterpenic phenol, is naturally occurring in various plants …