[HTML][HTML] Interleukin 6: at the interface of human health and disease
E Grebenciucova, S VanHaerents - Frontiers in immunology, 2023 - frontiersin.org
Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging
from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier …
from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier …
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
A network map of IL-33 signaling pathway
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central
role in the regulation of immune responses. Its release from epithelial and endothelial cells …
role in the regulation of immune responses. Its release from epithelial and endothelial cells …
[HTML][HTML] Hall of fame among pro-inflammatory cytokines: interleukin-6 gene and its transcriptional regulation mechanisms
Y Luo, SG Zheng - Frontiers in immunology, 2016 - frontiersin.org
Pro-inflammatory cytokines that are generated by immune system cells and mediate many
kinds of immune responses are kinds of endogenous polypeptides. They are also the …
kinds of immune responses are kinds of endogenous polypeptides. They are also the …
[HTML][HTML] Significance of interleukin (IL)-4 and IL-13 in inflammatory arthritis
M Iwaszko, S Biały, K Bogunia-Kubik - Cells, 2021 - mdpi.com
Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …
[HTML][HTML] IL-36, IL-37, and IL-38 cytokines in skin and joint inflammation: a comprehensive review of their therapeutic potential
The interleukin (IL)-1 family of cytokines is composed of 11 members, including the most
recently discovered IL-36α, β, γ, IL-37, and IL-38. Similar to IL-1, IL-36 cytokines are initiators …
recently discovered IL-36α, β, γ, IL-37, and IL-38. Similar to IL-1, IL-36 cytokines are initiators …
[HTML][HTML] Interleukin-6 signalling in health and disease
S Rose-John - F1000Research, 2020 - ncbi.nlm.nih.gov
Biochemically, interleukin-6 belongs to the class of four-helical cytokines. The cytokine can
be synthesised and secreted by many cells. It acts via a cell surface-expressed interleukin-6 …
be synthesised and secreted by many cells. It acts via a cell surface-expressed interleukin-6 …
[HTML][HTML] Role of IL-33 in inflammation and disease
AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders
HE Barksby, SR Lea, PM Preshaw… - Clinical & Experimental …, 2007 - academic.oup.com
Understanding cytokine immunobiology is central to the development of rational therapies
for destructive inflammatory diseases such as rheumatoid arthritis (RA) and periodontitis …
for destructive inflammatory diseases such as rheumatoid arthritis (RA) and periodontitis …
[HTML][HTML] Challenging the paradigm: anti-inflammatory interleukins and angiogenesis
AM Peluzzo, MV Autieri - Cells, 2022 - mdpi.com
Angiogenesis is a vital biological process, and neovascularization is essential for the
development, wound repair, and perfusion of ischemic tissue. Neovascularization and …
development, wound repair, and perfusion of ischemic tissue. Neovascularization and …