Interleukin-10 family cytokines immunobiology and structure
H Wei, B Li, A Sun, F Guo - Structural immunology, 2019 - Springer
Abstract The Interleukin (IL)-10 cytokine family includes IL-10, IL-19, IL-20, IL-22, IL-24, and
IL-26, which are considered as Class 2α-helical cytokines. IL-10 is the most important …
IL-26, which are considered as Class 2α-helical cytokines. IL-10 is the most important …
Blocking IL-17: a promising strategy in the treatment of systemic rheumatic diseases
C Rafael-Vidal, N Pérez, I Altabás, S Garcia… - International Journal of …, 2020 - mdpi.com
Systemic rheumatic diseases are a heterogeneous group of autoimmune disorders that
affect the connective tissue, characterized by the involvement of multiple organs, leading to …
affect the connective tissue, characterized by the involvement of multiple organs, leading to …
Interleukin-33 biology with potential insights into human diseases
G Palmer, C Gabay - Nature Reviews Rheumatology, 2011 - nature.com
Abstract Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is a nuclear
protein that is also released into the extracellular space, and thus acts as a dual-function …
protein that is also released into the extracellular space, and thus acts as a dual-function …
[PDF][PDF] Cytokines & their physiologic and pharmacologic functions in inflammation: A review.
PZ Shaikh - International Journal of Pharmacy & Life Sciences, 2011 - academia.edu
Inflammation is mediated by a variety of soluble factors, including a group of secreted
polypeptides known as cytokines. Inflammatory cytokines can be divided into two groups …
polypeptides known as cytokines. Inflammatory cytokines can be divided into two groups …
The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer
WE Naugler, M Karin - Trends in molecular medicine, 2008 - cell.com
Recent discoveries involving the cytokine interleukin (IL)-6 have originated from diverse
disciplines, revealing roles in biological processes that are likewise varied. The most novel …
disciplines, revealing roles in biological processes that are likewise varied. The most novel …
Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
PJ Murray - Current opinion in pharmacology, 2006 - Elsevier
Interleukin (IL)-10 performs an irreplaceable role in negatively regulating inflammation,
primarily through a mechanism that selectively blocks the expression of pro-inflammatory …
primarily through a mechanism that selectively blocks the expression of pro-inflammatory …
The IL-12 family of cytokines in infection, inflammation and autoimmune disorders
Cytokines are critical coordinators of the immune response necessary for resolving bacterial
and viral assaults on the immune system. In particular, the IL-12 family of cytokines are key …
and viral assaults on the immune system. In particular, the IL-12 family of cytokines are key …
Interleukin 26 skews macrophage polarization towards M1 phenotype by activating cJUN and the NF-κB pathway
Interleukin 26 (IL-26) is a new member of the IL-10 family that is highly expressed in
rheumatoid arthritis (RA). However, the functions of IL-26 produced by macrophages in RA …
rheumatoid arthritis (RA). However, the functions of IL-26 produced by macrophages in RA …
[PDF][PDF] Pro-versus anti-inflammatory cytokines: myth or reality
JM Cavaillon - Cellular And Molecular Biology-Paris-Wegmann-, 2001 - researchgate.net
Inflammation is characterized by an interplay between pro-and anti-inflammatory cytokines.
Cytokines are commonly classified in one or the other category: interleukin-1 (IL-1), tumor …
Cytokines are commonly classified in one or the other category: interleukin-1 (IL-1), tumor …
Not-so-sweet sixteen: the role of IL-16 in infectious and immune-mediated inflammatory diseases
WG Glass, RT Sarisky, AMD Vecchio - Journal of interferon & …, 2006 - liebertpub.com
Over the past two decades, our understanding of interleukin-16 (IL-16) has increased
substantially. Initial studies characterizing IL-16 as a chemotactic cytokine (but not a …
substantially. Initial studies characterizing IL-16 as a chemotactic cytokine (but not a …