Age-related alterations in default mode network: impact on working memory performance

F Sambataro, VP Murty, JH Callicott, HY Tan, S Das… - Neurobiology of …, 2010 - Elsevier
The default mode network (DMN) is a set of functionally connected brain regions which
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …

Longitudinal assessment of default-mode brain function in aging

J Persson, S Pudas, LG Nilsson, L Nyberg - Neurobiology of aging, 2014 - Elsevier
Age-related changes in the default-mode network (DMN) have been identified in prior cross-
sectional functional magnetic resonance imaging studies. Here, we investigated longitudinal …

A multivariate analysis of age-related differences in default mode and task-positive networks across multiple cognitive domains

CL Grady, AB Protzner, N Kovacevic… - Cerebral …, 2010 - academic.oup.com
We explored the effects of aging on 2 large-scale brain networks, the default mode network
(DMN) and the task-positive network (TPN). During functional magnetic resonance imaging …

Age differences in the intrinsic functional connectivity of default network subsystems

KL Campbell, O Grigg, C Saverino… - Frontiers in aging …, 2013 - frontiersin.org
Recent work suggests that the default mode network (DMN) includes two core regions, the
ventromedial prefrontal cortex and posterior cingulate cortex (PCC), and several unique …

Functional disintegration of the default mode network in prodromal Alzheimer's disease

KNH Dillen, HIL Jacobs, J Kukolja… - Journal of …, 2017 - content.iospress.com
Neurodegenerative brain changes can affect the functional connectivity strength between
nodes of the default-mode network (DMN), which may underlie changes in cognitive …

The longitudinal trajectory of default mode network connectivity in healthy older adults varies as a function of age and is associated with changes in episodic memory …

AM Staffaroni, JA Brown, KB Casaletto… - Journal of …, 2018 - Soc Neuroscience
The default mode network (DMN) supports memory functioning and may be sensitive to
preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory …

Age effect on the default mode network, inner thoughts, and cognitive abilities

K Mevel, B Landeau, M Fouquet, R La Joie… - Neurobiology of …, 2013 - Elsevier
Age-related effects on the default mode network (DMN) connectivity as measured at rest
using functional magnetic resonance imaging (fMRI) are now well described. Little is known …

Decreased default mode network connectivity correlates with age-associated structural and cognitive changes

D Vidal-Piñeiro, C Valls-Pedret… - Frontiers in aging …, 2014 - frontiersin.org
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray
(GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations …

Reduced resting-state brain activity in the “default network” in normal aging

JS Damoiseaux, CF Beckmann, EJS Arigita… - Cerebral …, 2008 - academic.oup.com
Normal aging is associated with cognitive decline. Functions such as attention, information
processing, and working memory are compromised. It has been hypothesized that not only …

The default mode network in healthy aging and Alzheimer′ s disease

K Mevel, G Chételat, F Eustache… - International journal of …, 2011 - Wiley Online Library
In the past decade, a “default mode network”(DMN) has been highlighted in neuroimaging
studies as a set of brain regions showing increased activity in task‐free state compared to …