Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …

Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …

Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …

During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …

Adaptive immune responses, characterized by T cells and B cells engaging and responding
to specific antigens, can be raised by biomaterials containing proteins, peptides, and other …

Autoimmune diseases occur when cells of the adaptive immune system incorrectly
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …

Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …