Engineering vaccines and niches for immune modulation
Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
Biomaterial-driven immunomodulation: cell biology-based strategies to mitigate severe inflammation and sepsis
JJM Lasola, H Kamdem, MW McDaniel… - Frontiers in …, 2020 - frontiersin.org
Inflammation is an essential component of a wide variety of disease processes and
oftentimes can increase the deleterious effects of a disease. Finding ways to modulate this …
oftentimes can increase the deleterious effects of a disease. Finding ways to modulate this …
Immunological principles regulating immunomodulation with biomaterials
The immune system has evolved to recognize and eliminate pathogens; this recognition
relies on the identification of structural molecular patterns within unique tissue …
relies on the identification of structural molecular patterns within unique tissue …
Biomaterials as local niches for immunomodulation
K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
Polymeric materials for immune engineering: Molecular interaction to biomaterial design
Biomaterials continue to evolve as complex engineered tools for interactively instructing
biological systems, aiding in the understanding and treatment of various disease states …
biological systems, aiding in the understanding and treatment of various disease states …
Biomolecular strategies to modulate the macrophage response to implanted materials
The material-induced foreign body response is a major challenge for implanted medical
devices. This review highlights recent developments in biomimetic approaches to create …
devices. This review highlights recent developments in biomimetic approaches to create …
Biomaterials as tools to decode immunity
HB Eppler, CM Jewell - Advanced Materials, 2020 - Wiley Online Library
The immune system has remarkable capabilities to combat disease with exquisite selectivity.
This feature has enabled vaccines that provide protection for decades and, more recently …
This feature has enabled vaccines that provide protection for decades and, more recently …
Immunomodulatory biomaterials
JL Dziki, SF Badylak - Current Opinion in Biomedical Engineering, 2018 - Elsevier
The immune system has long been recognized to play a critical role in the host defense
against pathogens, foreign bodies, and the tissue healing response following injury. More …
against pathogens, foreign bodies, and the tissue healing response following injury. More …
Key players in the immune response to biomaterial scaffolds for regenerative medicine
L Chung, DR Maestas Jr, F Housseau… - Advanced drug delivery …, 2017 - Elsevier
The compatibility of biomaterials is critical to their structural and biological function in
medical applications. The immune system is the first responder to tissue trauma and to a …
medical applications. The immune system is the first responder to tissue trauma and to a …
Harnessing biomaterials for immunomodulatory-driven tissue engineering
The immune system plays a crucial role during tissue repair and wound healing processes.
Biomaterials have been leveraged to assist in this in situ tissue regeneration process to …
Biomaterials have been leveraged to assist in this in situ tissue regeneration process to …