Vaccines and immunotherapies have provided enormous improvements for public health,
but there are fundamental disconnects between where most studies are performed—in cell …

Suppression of the recipient immune response is a common component of tissue and organ
transplantation strategies and has also been used as a method of mitigating the …

Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …

Activation of immune cells is an essential process in innate and adaptive immunity. A high
number of immune cell activation pathways have been discovered, which are stimulated via …

Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

The immune system protects organisms against endogenous and exogenous harm and
plays a key role in tissue development, repair and regeneration. Traditional …

Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …

Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

Adoptive immunotherapies based on the transfer of functional immune cells hold great
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …

Antigen presenting cells (APCs) such as macrophages and dendritic cells (DCs) play a
crucial role in orchestrating immune responses against foreign materials. The activation …