This concise tutorial review provides a description of the current state of the art in the
application of time-of flight based secondary ion mass spectrometry (TOF-SIMS) in the field …

Time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging is an analytical
technique rapidly expanding in use in biological studies. This technique is based on high …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has unique capabilities in the
area of high-resolution mass spectrometric imaging of biological samples. The technique …

Time of flight secondary ion mass spectrometry (ToF-SIMS) has the unique ability to
simultaneously obtain chemical information (elemental and molecular) with its spatial …

Recent technological and methodological improvements have greatly enhanced the
sensitivity of the Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS), thus making …

In principle mass spectral imaging has enormous potential for discovery applications in
biology. The chemical specificity of mass spectrometry combined with spatial analysis …

Secondary ion mass spectrometry (SIMS) is a technique capable of imaging tissues, single
cells, and microbes revealing chemical species with sub-micrometer spatial resolution. The …

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides a method for the
detection of native and exogenous compounds in biological samples on a cellular scale …

Secondary ion mass spectrometry (SIMS) has been increasingly recognized as a powerful
technique for visualizing molecular architectures in the fields of neurobiology and cell …

This article is a concise review of the application of secondary ion mass spectrometry (SIMS)
to the imaging of biological cells. The paper covers the various advantages and …