Correlation of the Taq 1 dopamine D2 receptor gene and percent body fat in obese and screened control subjects: a preliminary report

ALC Chen, K Blum, TJH Chen, J Giordano… - Food & function, 2012 - pubs.rsc.org
While there is a considerable body of literature correlating the role of dopaminergic genes
and obesity, body mass index, body type, overeating, carbohydrate binging, energy …

Variant alleles of the D2 dopamine receptor gene and obesity

MR Spitz, MA Detry, P Pillow, Y Hu, CI Amos… - Nutrition Research, 2000 - Elsevier
The mesocorticolimbic dopaminergic reward pathways have a role in the neuromodulation
of appetite. There are data supporting a role of allelic variants of the D2 dopamine receptor …

D2 dopamine receptor gene and obesity

EP Noble, RE Noble, T Ritchie… - … Journal of Eating …, 1994 - Wiley Online Library
The prevalence of Taql A D2 dopamine receptor (DRD2) alleles was determined in 73
obese women and men. In this sample with a mean body mass index of 35.1, the A1 (minor) …

The dopamine D2 receptor (DRD2) as a major gene in obesity and height

DE Comings, SD Flanagan, G Dietz… - … medicine and metabolic …, 1993 - Elsevier
Dopamine plays a major role in the regulation of appetite and growth hormone.
Dopaminergic agonists suppress appetite and dopamine D 2 receptor antagonists enhance …

The Taq IA and Ser311 Cys polymorphisms in the dopamine D2 receptor gene and obesity.

A Southon, K Walder, AM Sanigorski… - Diabetes, nutrition & …, 2003 - europepmc.org
Dopamine D2 receptors (DRD2) in the central nervous system are involved in the regulation
of feeding. It remains to be elucidated if mutations in the DRD2 gene contribute to the …

Increased prevalence of the Taq I A1allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report

K Blum, ER Braverman, RC Wood, J Gill… - Pharmacogenetics …, 1996 - journals.lww.com
In order to investigate the prevalence of the Taq IA 1 allele of the dopamine receptor gene
(DRD 2) in obesity with and without comorbid substance use disorder, a total of 40 patients …

D4 dopamine receptor gene exon III polymorphism and obesity risk

WSC Poston, M Ericsson, J Linder, CK Haddock… - Eating and Weight …, 1998 - Springer
Many genes have been identified that may play a role in increasing individua susceptibility
to obesity. Reduced dopamine function appears to play a role in dysfunctiona eating …

Association of dopamine D2 receptor polymorphisms Ser311Cys and TaqIA with obesity or type 2 diabetes mellitus in Pima Indians

CP Jenkinson, R Hanson, K Cray, C Wiedrich… - International journal of …, 2000 - nature.com
OBJECTIVES: To investigate whether (a) variants within the dopamine D2 receptor gene
(DRD2) are associated with obesity and type 2 diabetes in Pima Indians, and (b) whether …

A meta-analysis of the relationship between brain dopamine receptors and obesity: a matter of changes in behavior rather than food addiction?

D Benton, HA Young - International journal of obesity, 2016 - nature.com
Addiction to a wide range of substances of abuse has been suggested to reflect a 'Reward
Deficiency Syndrome'. That is, drugs are said to stimulate the reward mechanisms so …

No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity

A Hinney, J Schneider, A Ziegler… - American journal of …, 1999 - Wiley Online Library
Family and twin studies suggest a genetic contribution to the etiology of anorexia nervosa
(AN) and obesity. Genes involved in weight regulation can be considered as candidate …