Transcriptome-wide high-throughput m6A sequencing of differential m6A methylation patterns in the human rheumatoid arthritis fibroblast-like synoviocytes cell line …
H Jiang, K Cao, C Fan, X Cui, Y Ma… - Journal of Inflammation …, 2021 - Taylor & Francis
Introduction: N6-methyladenosine (m6A) is the most frequent internal modification in
eukaryotic mRNAs and is closely related to the occurrence and development of many …
eukaryotic mRNAs and is closely related to the occurrence and development of many …
Comprehensive Analysis and Functional Characteristics of Differential Expression of N6‐Methyladenosine Methylation Modification in the Whole Transcriptome of …
L Wan, J Liu, C Huang, Z Zhu, K Wang… - Mediators of …, 2022 - Wiley Online Library
N6‐methyladenosine (m6A) modification is the most prevalent chemical modification in
eukaryotic mRNA and is associated with the development of various immune diseases …
eukaryotic mRNA and is associated with the development of various immune diseases …
Characterization of immune microenvironment infiltration and m6A regulator-mediated RNA methylation modification patterns in osteoarthritis
Y Ouyang, Y Tu, S Chen, H Min, Z Wen… - Frontiers in …, 2022 - frontiersin.org
Background Few studies have been reported the potential role of N6-methyladenosine
(m6A) modification in osteoarthritis (OA). We investigated the patterns of m6A modification in …
(m6A) modification in osteoarthritis (OA). We investigated the patterns of m6A modification in …
Genome-Wide Identification of N6-Methyladenosine (m6A) SNPs Associated With Rheumatoid Arthritis
XB Mo, YH Zhang, SF Lei - Frontiers in genetics, 2018 - frontiersin.org
Previous large scale genome-wide association studies (GWAS) have identified more than
one hundred susceptibility loci for rheumatoid arthritis (RA)(Stahl et al., 2010; Eyre et al …
one hundred susceptibility loci for rheumatoid arthritis (RA)(Stahl et al., 2010; Eyre et al …
[HTML][HTML] Emerging roles and mechanism of m6A methylation in rheumatoid arthritis
Y Xu, W Liu, L Ren - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Rheumatoid arthritis (RA) is a multifaceted autoimmune disease characterized by systemic
inflammation, affecting both articular and extra-articular structures. This condition results in …
inflammation, affecting both articular and extra-articular structures. This condition results in …
The m6A/m1A/m5C-Related methylation modification patterns and Immune landscapes in Rheumatoid Arthritis and Osteoarthritis revealed by microarray and single …
H Zheng, Y Aihaiti, Y Cai, Q Yuan, M Yang… - Journal of …, 2023 - Taylor & Francis
Purpose The goal of this study was to explore the expression characteristics of RNA
modification-related genes, reveal immune landscapes and identify novel potential …
modification-related genes, reveal immune landscapes and identify novel potential …
N6 -Methyladenosine and Rheumatoid Arthritis: A Comprehensive Review
S Wu, XF Li, YY Wu, SQ Yin, C Huang, J Li - Frontiers in immunology, 2021 - frontiersin.org
Rheumatoid arthritis (RA), one of the most common autoimmune diseases, is characterized
by immune cell infiltration, fibroblast-like synovial cell hyperproliferation, and cartilage and …
by immune cell infiltration, fibroblast-like synovial cell hyperproliferation, and cartilage and …
M6A methylation modification in autoimmune diseases, a promising treatment strategy based on epigenetics
Y Huang, Q Xue, J Chang, Y Wang, C Cheng… - Arthritis Research & …, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) methylation modification is involved in the
regulation of various biological processes, including inflammation, antitumor, and antiviral …
regulation of various biological processes, including inflammation, antitumor, and antiviral …
N6-methyladenosine RNA modification in inflammation: roles, mechanisms, and applications
J Luo, T Xu, K Sun - Frontiers in cell and developmental biology, 2021 - frontiersin.org
N6-methyladenosine (m6A) is the most prevalent internal mRNA modification. m6A can be
installed by the methyltransferase complex and removed by demethylases, which are …
installed by the methyltransferase complex and removed by demethylases, which are …
Diagnostic gene signatures and aberrant pathway activation based on m6A methylation regulators in rheumatoid arthritis
Q Geng, X Cao, D Fan, X Gu, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Purpose Rheumatoid arthritis (RA) is a chronic autoimmune disease (AD) characterized by
persistent synovial inflammation, bone erosion and progressive joint destruction. This …
persistent synovial inflammation, bone erosion and progressive joint destruction. This …
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