Hypertension is one of the most important risk factors and a leading cause of death from
cardiovascular and cerebrovascular diseases. Based on numerous previous studies …

The renin-angiotensin system (RAS) has been extensively studied in the past decades as an
important mediator of hypertension and hypertensive end-organ damage. Originally, the …

Hypertension remains one of the largest human health problems, because hypertensive
patients carry increased risk for ischemic heart disease, stroke, atherosclerosis, and renal …

Hypertension is a polygenic and multi‐factorial disorder that is extremely prevalent in
western societies, and thus has received a great deal of attention by the research …

Researchers continue to be fascinated with the renin-angiotensin system (RAS) more than
100 yr after its discovery because of its powerful role in controlling sodium balance, body …

The renin-angiotensin system plays an important role in the control of blood pressure (BP)
and renal function. To illuminate the importance of renin in the context of a disease …

Since the discovery of renin as a pressor substance in 1898, the renin-angiotensin (RAS)
system has been extensively studied because it remains a prime candidate as a causative …

With advances in genetic manipulation and molecular biological and physiological
techniques, the mouse has become the animal model of choice for studying the genetic …

The renin–angiotensin system (RAS) in the brain is a critical determinant of blood pressure,
but the mechanisms regulating RAS activity in the brain remain unclear. Expression of brain …

The renin-angiotensin system (RAS) is well-recognized as one of the oldest and most
important regulators of arterial blood pressure, cardiovascular, and renal function. New …