Transduction with recombinant, replication-defective adenovirus (AdV) vectors encoding a
transgene is an efficient method for gene transfer into murine or human dendritic cells (DC) …

Several studies have shown that vaccine therapy using dendritic cells (DCs) pulsed with
specific tumor antigen peptides can effectively induce antitumor immunity. Peptide-pulsed …

Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential
target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) …

Dendritic cells (DC) are among the most potent antigen-presenting cells known and play an
important role in the initiation of antigen-specific T-lymphocyte responses. Several recent …

Dendritic cells (DCs) are the most effective antigen presenting cells (APCs) to elicit both
primary and secondary T-cell response that is critical for antitumor immunity and elimination …

In recent years, vaccination strategies using antigen-presenting cells (APC) have been
under investigation. Antigen delivery using genetic immunization through ex vivo …

Evaluation of the potential role of dendritic cells (DCs) as adjuvants for tumor vaccination
has focused primarily on techniques that load DCs with peptide tumor antigens. Our aim has …

Dendritic cells (DC) are highly efficient antigen presenting cells being actively evaluated as
vaccine components. A number of studies have shown adenovirus-mediated gene transfer …

Dendritic cells (DCs) are potent antigen presenting cells that exist in virtually every tissue,
and from which they capture antigens and migrate to secondary lymphoid organs where …

Effective antitumor immunity requires the generation and persistence of functional tumor-
specific T-cell responses. Among the critical factors that often control these responses is how …