Due to its wide range of deleterious effects on the unborn baby, knowledge on the
disposition of ethanol in the maternal-fetal unit is critical. This review summarizes and …

The pharmacokinetics of ethanol and its metabolite, acetaldehyde, were determined in the
third-trimester pregnant guinea pig (56–59 days gestation) for oral intubation of four doses of …

The disposition of ethanol was studied in third-trimester pregnant guinea pigs (56–59 days
gestational age) following maternal administration of ethanol, 0.5 g/kg total body weight, by …

To evaluate the pharmacokinetics of ethanol in the early second trimester of pregnancy,
ethanol concentrations simultaneously measured in the maternal blood (EtOH-MB) and in …

Introduction Ethanol has been used for years in neonatal and infant liquid medications, yet
the pharmacokinetics, pharmacodynamics, and safety of ethanol in this vulnerable …

Three cynomolgus and 6 rhesus monkeys (106-160 days gestational age) were
administered ethanol (0.8-1.5 g/kg iv) over a 30-min period. Blood samples were drawn …

Maternal blood alcohol levels, weight gain during pregnancy, parturition time, perinatal
mortality, and postnatal growth of offspring were compared in groups of pregnant rats fed …

The disposition of ethanol and its metabolite, acetaldehyde, and the activity of alcohol
dehydrogenase (ADH) and aldehyde dehydrogenases (ALOH) were determined in the third …

A commonly observed result of ethanol administration to experimental animals is a reduction
in voluntary dietary intake. The purpose of this investigation was to examine the role of this …

The pattern of ethanol and acetaldehyde appearance in blood after an oral ethanol gavage
(4 g/kg body wt) was not different at 12 or 21 days' gestation compared to virgin rats. Five …