Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1

S Fukuda, S Kaga, L Zhan, D Bagchi, DK Das… - Cell biochemistry and …, 2006 - Springer
In our study, resveratrol (polyphenol) has been identified as a very important stimulus/agent
for the induction of new vessel growth. Occlusion of a main coronary depletes the blood …

Resveratrol attenuates myocardial ischemia/reperfusion injury through up-regulation of vascular endothelial growth factor B

L Yang, Y Zhang, M Zhu, Q Zhang, X Wang… - Free Radical Biology …, 2016 - Elsevier
The objective was to examine the protective effect of resveratrol (RSV) on myocardial
ischemia/reperfusion (IR) injury and whether the mechanism was related to vascular …

Resveratrol induces nuclear factor-κB activity in human cardiac cells

X Palomer, E Capdevila-Busquets… - International journal of …, 2013 - Elsevier
Background Resveratrol is a grape polyphenol that prevents cardiac hypertrophy and
protects the heart from ischemic injury, metabolic dysregulation, and inflammatory processes …

Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia

MP Robich, RM Osipov, R Nezafat, J Feng… - Circulation, 2010 - Am Heart Assoc
Background—Resveratrol may provide protection against coronary artery disease. We
hypothesized that supplemental resveratrol will improve cardiac perfusion in the ischemic …

Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway

L Feng, J Ren, Y Li, G Yang, L Kang, S Zhang… - Free radical …, 2019 - Taylor & Francis
According to our previous results, resveratrol (RSV, 3, 5, 4-trihydroxystilbene), a naturally
polyphenolic phytoalexin, could attenuate myocardial ischemia/reperfusion injury through …

Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart

S Das, VKT Alagappan, D Bagchi, HS Sharma… - Vascular …, 2005 - Elsevier
Existing evidence indicates that resveratrol, a red wine and grape-derived polyphenolic
antioxidant, can pharmacologically precondition the heart in a nitric oxide (NO)-dependent …

[HTML][HTML] Resveratrol attenuates the inflammatory reaction induced by ischemia/reperfusion in the rat heart

X Cong, Y Li, N Lu, Y Dai… - Molecular …, 2014 - spandidos-publications.com
The role of resveratrol (Res) in inflammation induced by ischemia/reperfusion is not well
understood. The aim of the present study was to investigate whether Res modulates …

[HTML][HTML] Resveratrol improves cardiac function and left ventricular fibrosis after myocardial infarction in rats by inhibiting NLRP3 inflammasome activity and the TGF-β1 …

J Jiang, X Gu, H Wang, S Ding - PeerJ, 2021 - peerj.com
Background Several studies have shown that resveratrol (RES), a naturally occurring
polyphenol found in many plants, is beneficial for preventing cardiovascular diseases …

[HTML][HTML] Resveratrol prevents Ang II-induced cardiac hypertrophy by inhibition of NF-κB signaling

E Ma, C Wu, J Chen, D Wo, D Ren, H Yan… - Biomedicine & …, 2023 - Elsevier
Background Pathological cardiac hypertrophy is a hallmark of various cardiovascular
diseases (CVD) including chronic heart failure (HF) and an important target for the treatment …

[HTML][HTML] Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-κB signaling pathway

J Li, C Xie, J Zhuang, H Li, Y Yao… - Molecular …, 2015 - spandidos-publications.com
It has been previously reported that Toll‑like receptor 4 (TLR4)/NF‑κB signaling mediates
early inflammation during myocardial ischemia and reperfusion. It has additionally been …