Recent research progress has given detailed knowledge on the molecular pathogenesis of
Alzheimer's disease (AD), which has been translated into an intense, ongoing development …

Intense research during the past decade has aimed at dissecting the molecular
pathogenesis of Alzheimer's disease (AD). Primarily, the focus has been directed towards …

Alzheimer's disease is an age-related neurodegenerative disorder that results in
progressive cognitive impairment and death. The accumulation of β-amyloid (Aβ) in specific …

Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …

Amyloid plaques are composed primarily of amyloid-beta (Aβ) peptides derived from
proteolytic cleavage of amyloid precursor protein (APP) and are considered to play a pivotal …

The development of validated, qualified, and standardized biomarkers for Alzheimer's
disease (AD) that allow for an early presymptomatic diagnosis and discrimination …

The identification and characterization of amyloid-β (Aβ) and tau as the main pathological
substrates of Alzheimer's disease (AD) have driven many efforts in search for suitable …

Research progress has given detailed knowledge on the molecular pathogenesis of
Alzheimer's disease (AD), which has been translated into an ongoing development of …

Aggregation of amyloid-β (Aβ) into oligomers, fibrils, and plaques is central in the molecular
pathogenesis of Alzheimer's disease (AD), and is the main focus of AD drug development …

Diagnosis and monitoring of sporadic Alzheimer's disease (AD) have long depended on
clinical examination of individuals with end-stage disease. However, upcoming anti-AD …