Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

Mitochondria play a central role in cellular energy metabolism. Mitochondrial genome
(mtDNA) is specific with a maternal transmission. Defects of mtDNA, both quantitative …

Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …

Mitochondria play a pivotal role in cellular metabolism and are important determinants of
embryonic development. Mitochondrial function and biogenesis rely on an intricate …

Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death.
They possess their own multicopy genome, which is maternally transmitted. Mitochondria …

Reproduction is an energy-requiring process, not only for the participants but also for their
germ cells. Mitochondrial misbehavior could imperil many facets of the reproductive process …

Mitochondria are maternally inherited, semi-autonomous organelles with their own genomes
(mtDNA), largely responsible for the generation of energy in the form of cellular ATP …

The preimplantation embryo is sensitive to its environment and, despite having some
plasticity to adapt, environmental perturbations can impair embryo development, metabolic …

Many diseases have their origins at the time of fertilization when the oocyte and sperm unite.
These diseases can arise from the subsequent transmission of genetic and epigenetic …

Mitochondria are essential organelles found in most eukaryotic cells [1, 2]. They play
important roles not only in the production of cellular energy but also in metabolic [3], immune …