The mitochondrial challenge: Disorders and prevention strategies

E Korchivaia, Y Silaeva, I Mazunin, I Volodyaev - Biosystems, 2023 - Elsevier
This short review provides basic knowledge on mitochondrial inheritance, its disorders, and
potential ways to overcome them in human reproductive medicine. The latter are currently …

Molecular control of mitochondrial function in developing rhesus monkey oocytes and preimplantation-stage embryos

NR Mtango, AJ Harvey, KE Latham… - Reproduction, Fertility …, 2008 - CSIRO Publishing
The mitochondrion undergoes significant functional and structural changes, as well as an
increase in number, during preimplantation embryonic development. The mitochondrion …

mtDNA mutations variously impact mtDNA maintenance throughout the human embryofetal development

J Steffann, S Monnot, JP Bonnefont - Clinical Genetics, 2015 - Wiley Online Library
Mitochondria are the largest generator of ATP in the cell. It is therefore expected that energy‐
requiring processes such as oocyte maturation, early embryonic or fetal development, would …

Mitochondria and reproduction: possibilities for testing and treatment.

SG Kristensen, P Humaidan, K Coetzee - Panminerva medica, 2018 - europepmc.org
Mitochondria, known as the energy factories in all cells, are key regulators of multiple vital
cellular processes and affect all aspects of mammalian reproduction, being essential for …

Mitochondria as a biomarker for IVF outcome

J Kim, E Seli - Reproduction, 2019 - rep.bioscientifica.com
Mitochondria play an essential role in generating energy for embryo development and
maintaining embryo metabolism through key cellular functions including ion homeostasis …

The role of mitochondrial function in the oocyte and embryo

R Dumollard, M Duchen, J Carroll - Current topics in developmental …, 2007 - Elsevier
Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Mitochondrial function of human embryo: Decline in their quality with maternal aging

S Hashimoto, Y Morimoto - Reproductive Medicine and Biology, 2022 - Wiley Online Library
Background Female fertility declines with age, due to increased chromosomal aneuploidy
and possible reduced mitochondrial function in the embryo. Methods This review outlines …

Alterations in mitochondrial membrane potential during preimplantation stages of mouse and human embryo development

BM Acton, A Jurisicova, I Jurisica… - MHR: Basic science of …, 2004 - academic.oup.com
Mitochondria are cellular organelles regulating metabolism and cell death pathways. This
study examined changes in mitochondrial membrane potential (ΔΨm) throughout the stages …

[HTML][HTML] Mitochondria in reproduction

MH Kang, YJ Kim, JH Lee - Clinical and Experimental …, 2023 - ncbi.nlm.nih.gov
In reproduction, mitochondria produce bioenergy, help to synthesize biomolecules, and
support the ovaries, oogenesis, and preimplantation embryos, thereby facilitating healthy …

Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence

J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …