Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …

Mitochondria are the most abundant organelles in mammalian oocytes and early embryos.
The central role of mitochondria in the establishment of developmental competence of …

This review examines current understanding of mammalian mitochondria and mitochondrial
DNA in the light of new reproductive technologies. Mitochondria are central to ageing …

Mitochondria play a key role in a number of physiological events during all stages of life,
including the very first stages following fertilization. It is, therefore, important to understand …

Mitochondrial diseases are distinct types of metabolic and/or neurologic abnormalities that
occur as a consequence of dysfunction in oxidative phosphorylation, affecting several …

This introduction reviews the background of mitochondrial transplantation. Its goals are to
provide both basic and clinical insights into mitochondria and reproduction. The articles will …

Our research has focused on promoting the development of compromised embryos by
transferring presumably normal ooplasm, including mitochondria, to oocytes during …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Mitochondria play a fundamental role during development of the female germline. They are
fragmented, round, and small. Despite these characteristics suggesting that they are …

Objective: To determine the effect of mutant mitochondria on preimplantation embryo
development and of preimplantation embryo development on the survival of mutant …