Oocyte mitochondria are increased in number, smaller, and rounder in appearance than
mitochondria in somatic cells. Moreover, mitochondrial numbers and activity are narrowly …

Study question Does mitochondrial gene expression differ between good and poor quality
oocytes and can mitochondria be targeted in vitro to alter oocyte quality? Summary answer …

The mammalian embryo requires an increasing amount of energy as it develops during the
embryonic and foetal stages. The main production mechanism of adenosine triphosphate …

Mitochondria play a vital role in embryo development. They are the principal site of energy
production and have various other critical cellular functions. Despite the importance of this …

Mitochondria transfer techniques were first designed to prevent the transmission of diseases
due to mutations in mtDNA, as these organelles are exclusively transmitted to the offspring …

Many of the assisted reproductive techniques associated with maternal aging, disease
states, or implantation failure aim to correct poor developmental capacity. These techniques …

Mitochondrial biogenesis and function are essential for proper embryo development;
however, these processes have not been further studied during the placentation period …

Objective To assess the mitochondrial DNA (mtDNA) load and variation in human oocytes
and during preimplantation embryo development using specimens donated for research …

STUDY QUESTION Does the amount of mitochondrial DNA (mtDNA) in blastocyst biopsy
specimens have the potential to serve as a biomarker of euploid embryo implantation ability …

Oocyte quality depends on nuclear and cytoplasmic factors. Because structure and
subcellular localization of mitochondria significantly change during oocyte maturation, their …