Vaccination is one of the most effective and cost-benefit interventions that prevent the
mortality and reduce morbidity from infectious pathogens. However, the licensed influenza …

Influenza vaccines are the mainstay of efforts to reduce the substantial health burden from
seasonal influenza. Inactivated influenza vaccines have been available since the 1940s and …

Influenza Vaccines for the Future | New England Journal of Medicine Skip to main content The
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The medical and economic burden associated with annual influenza activity is well known
and well documented. Yearly updated influenza vaccines are available to combat the …

Background The efficacy of influenza vaccines may vary from year to year, depending on a
variety of factors, and may differ for inactivated and live attenuated vaccines. Methods We …

Influenza viruses remain a constant burden in humans, causing millions of infections and
hundreds of thousands of deaths each year. Current influenza virus vaccine modalities …

Several strategies are being pursued to increase the quality and quantity of influenza
vaccines that are used on an annual basis including increasing the immunogenicity of …

Influenza virus causes an acute respiratory infection in humans. Frequent point mutations in
the influenza genome and occasional exchange of genetic segments between virus strains …

Vaccination is the most effective way to reduce the impact of epidemic as well as pandemic
influenza. However, the licensed inactivated influenza vaccine induces strain-specific …

Influenza vaccine preparations have been administered to humans since the late 1930s,
and the diversity of approaches in licensed trivalent seasonal or monovalent pandemic …