Introduction: The licensed seasonal influenza vaccines predominantly induce neutralizing
antibodies against immunodominant hypervariable epitopes of viral surface proteins, with …

Fears of a potential pandemic due to A (H5N1) viruses have focussed new attention on our
current vaccines, their shortcomings, and concerns regarding global vaccine supply in a …

Influenza vaccines have been available for over 80 years. They have contributed to
significant reductions in influenza morbidity and mortality. However, there have been …

Influenza viruses infect approximately 20% of the global population annually, resulting in
hundreds of thousands of deaths. While there are Food and Drug Administration (FDA) …

Influenza is a highly infectious airborne disease with an important epidemiological and
societal burden; annual epidemics and pandemics have occurred since ancient times …

Despite use of influenza vaccines for more than 65 y, influenza and its complications are a
major cause of morbidity and mortality worldwide. Most deaths during influenza virus …

Data supporting the use of the live attenuated influenza vaccine (LAIV) in children and
adults is reviewed, and the development and characteristics of the vaccine are summarized …

Numerous modern technological and scientific advances have changed the vaccine
industry. However, nearly 70 years of influenza vaccine usage have passed without …

Despite the availability of an inactivated vaccine that has been licensed for> 50 years, the
influenza virus continues to cause morbidity and mortality worldwide. Constant evolution of …

The numerous influenza infections that occur every year present a major public health
problem. Influenza vaccines are important for the prevention of the disease; however, their …