Efficacy of FLU-v, a broad-spectrum influenza vaccine, in a randomized phase IIb human influenza challenge study

O Pleguezuelos, E James, A Fernandez, V Lopes… - NPJ vaccines, 2020 - nature.com
FLU-v, developed by PepTcell (SEEK), is a peptide vaccine aiming to provide a broadly
protective cellular immune response against influenza A and B. A randomized, double-blind …

A pragmatic randomized feasibility trial of influenza vaccines

ND Johansen, D Modin, J Nealon, S Samson… - NEJM …, 2023 - evidence.nejm.org
Background The relative vaccine effectiveness (rVE) of high-dose quadrivalent influenza
vaccines (QIV-HD) versus standard-dose quadrivalent influenza vaccines (QIV-SD) against …

Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004–2005 season to the 2006–2007 season

EA Belongia, BA Kieke, JG Donahue… - The Journal of …, 2009 - academic.oup.com
Background. We estimated the effectiveness of inactivated influenza vaccines for the
prevention of laboratory-confirmed, medically attended influenza during 3 seasons with …

Understanding influenza transmission, immunity and pandemic threats

JD Mathews, JM Chesson, JM McCaw… - Influenza and other …, 2009 - Wiley Online Library
The current pandemic threat can be best understood within an ecological framework that
takes account of the history of past pandemics caused by influenza A, the relationships …

Influenza vaccines: good, but we can do better

CI Paules, AS Fauci - The Journal of infectious diseases, 2019 - academic.oup.com
Influenza viruses, particularly influenza A viruses, cause a substantial degree of morbidity
and mortality worldwide and are a persistent threat to global health. Influenza viruses have 2 …

Prevention and control of seasonal influenza with vaccines. Recommendations of the Advisory Committee on Immunization Practices--United States, 2013-2014

Centers for Disease Control and … - MMWR …, 2013 - pubmed.ncbi.nlm.nih.gov
This report updates the 2012 recommendations by CDC's Advisory Committee on
Immunization Practices (ACIP) regarding the use of influenza vaccines for the prevention …

Influenza virus

FG Hayden, P Palese - Clinical virology, 2009 - Wiley Online Library
Homologous recombination between corresponding RNA segments of different influenza
viruses has not been observed, in contrast to the high frequency of recombination observed …

Live attenuated influenza vaccine (FluMist®; fluenz™) a review of its use in the prevention of seasonal influenza in children and adults

NJ Carter, MP Curran - Drugs, 2011 - Springer
Live attenuated influenza vaccine (LAIV) is an intranasally administered trivalent, seasonal
influenza vaccine that contains three live influenza viruses (two type A [H1N1 and H3N2 …

Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review

T Jefferson, S Smith, V Demicheli, A Harnden, A Rivetti… - The lancet, 2005 - thelancet.com
Background We aimed to assess evidence of efficacy and effectiveness of live attenuated
and inactivated influenza vaccines in children up to 16 years of age. Methods We searched …

Safety, efficacy, and immunogenicity of an inactivated influenza vaccine in healthy adults: a randomized, placebo-controlled trial over two influenza seasons

LA Jackson, MJ Gaglani, HL Keyserling, J Balser… - BMC infectious …, 2010 - Springer
Background Seasonal influenza imposes a substantial personal morbidity and societal cost
burden. Vaccination is the major strategy for influenza prevention; however, because …