A dual, systematic approach to malaria diagnostic biomarker discovery
S Yerlikaya, EDA Owusu, A Frimpong… - Clinical Infectious …, 2022 - academic.oup.com
Background The emergence and spread of Plasmodium falciparum parasites that lack
HRP2/3 proteins and the resulting decreased utility of HRP2-based malaria rapid diagnostic …
HRP2/3 proteins and the resulting decreased utility of HRP2-based malaria rapid diagnostic …
Assessing performance of HRP2 antigen detection for malaria diagnosis in Mozambique
MM Plucinski, B Candrinho, M Dimene… - Journal of clinical …, 2019 - Am Soc Microbiol
Rapid diagnostic tests (RDTs) that detect the Plasmodium falciparum-specific histidine-rich
protein 2 (PfHRP2) antigen are the primary methods for malaria diagnosis in Mozambique …
protein 2 (PfHRP2) antigen are the primary methods for malaria diagnosis in Mozambique …
The accuracy of the first response histidine-rich protein2 rapid diagnostic test compared with malaria microscopy for guiding field treatment in an outbreak of …
ASB Ghouth, FM Nasseb, KH Al-Kaldy - Tropical Parasitology, 2012 - journals.lww.com
Background: Recent WHO guidelines recommended a universal “test and treat” strategy for
malaria mainly by use of the rapid diagnostic test (RDT) in all areas. There are concerns …
malaria mainly by use of the rapid diagnostic test (RDT) in all areas. There are concerns …
Usefulness of Plasmodium falciparum-specific rapid diagnostic tests for assessment of parasite clearance and detection of recurrent infections after artemisinin-based …
Background Rapid diagnostic test (RDT) is an important tool for parasite-based malaria
diagnosis. High specificity of RDTs to distinguish an active Plasmodium falciparum infection …
diagnosis. High specificity of RDTs to distinguish an active Plasmodium falciparum infection …
Limitations of rapid diagnostic testing in patients with suspected malaria: a diagnostic accuracy evaluation from Swaziland, a low-endemicity country aiming for …
N Ranadive, S Kunene, S Darteh… - Clinical Infectious …, 2017 - academic.oup.com
Abstract Background. The performance of Plasmodium falciparum–specific histidine-rich
protein 2–based rapid diagnostic tests (RDTs) to evaluate suspected malaria in low …
protein 2–based rapid diagnostic tests (RDTs) to evaluate suspected malaria in low …
Limitations of rapid diagnostic tests in malaria surveys in areas with varied transmission intensity in Uganda 2017-2019: Implications for selection and use of HRP2 …
AB Bosco, JI Nankabirwa, A Yeka, S Nsobya, K Gresty… - PloS one, 2020 - journals.plos.org
Background Plasmodium falciparum histidine-rich protein 2 (HRP2)-based rapid diagnostic
tests (RDTs) are exclusively recommended for malaria diagnosis in Uganda; however, their …
tests (RDTs) are exclusively recommended for malaria diagnosis in Uganda; however, their …
Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests
J Baker, MF Ho, A Pelecanos, M Gatton, N Chen… - Malaria journal, 2010 - Springer
Background Accurate diagnosis is essential for prompt and appropriate treatment of malaria.
While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the …
While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the …
Development of a stable positive control to be used for quality assurance of rapid diagnostic tests for malaria
I Versteeg, PF Mens - Diagnostic microbiology and infectious disease, 2009 - Elsevier
The objective of this study is to develop and evaluate a simple, cheap, and stable positive
control for the quality control and quality assurance (QA) of rapid diagnostic tests (RDT) for …
control for the quality control and quality assurance (QA) of rapid diagnostic tests (RDT) for …
HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions
A Kong, SA Wilson, Y Ah, D Nace, E Rogier, M Aidoo - Malaria Journal, 2021 - Springer
Abstract Background The Plasmodium falciparum antigen histidine rich protein 2 (HRP2) is
a preferred target for malaria rapid diagnostic tests (RDTs) because of its abundant …
a preferred target for malaria rapid diagnostic tests (RDTs) because of its abundant …
[HTML][HTML] Association between HRP–2/pLDH rapid diagnostic test band positivity and malaria–related anemia at a peripheral health facility in Western Uganda
R Boyce, R Reyes, M Ntaro, E Mulogo… - Journal of Global …, 2015 - ncbi.nlm.nih.gov
The detection of severe malaria in resource–constrained settings is often difficult because of
requirements for laboratory infrastructure and/or clinical expertise. The aim of this study …
requirements for laboratory infrastructure and/or clinical expertise. The aim of this study …