Lung cancer is the leading cause of cancer mortality worldwide. There have been only slight
improvements in early diagnosis and survival, reflecting limited advances in screening and …

Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

A growing number of studies investigating the association between Single Nucleotide
Polymorphisms (SNPs) and lung cancer risk have been published since over a decade ago …

Background Genetic variation increases the risk of lung cancer, but the extent to which
smoking amplifies this effect remains unknown. Therefore, we aimed to investigate the risk of …

Background Lung cancer is the leading cause of cancer mortality worldwide. Tobacco
smoking is its primary cause, and yet the precise molecular alterations induced by smoking …

Background Personalizing non-small-cell lung cancer (NSCLC) therapy toward oncogene
addicted pathway inhibition is effective. Hence, the ability to determine a more …

We carried out a genome-wide association study of lung cancer (3,259 cases and 4,159
controls), followed by replication in 2,899 cases and 5,573 controls. Two uncorrelated …

Background Differences in carcinogenesis and therapeutic efficacy according to ethnicity
have been reported for lung cancer, and understanding differences in genetic mutation …

To identify the genetic factors that influence overall survival in never smokers who have non–
small cell lung carcinoma (NSCLC), we conducted a consistency meta-analysis study using …

Purpose Adenocarcinoma is the most dominant type of lung cancer in never-smoker
patients. The risk alleles from genome-wide association studies have small odds ratios and …