A series of 3-aryl-5-acyloxymethyl-5, 6-dihydro-2H-pyran-2-ones, related to highly
antifungally active butenolides, was synthesized via cyclization of substituted δ-hydroxy …

A series of racemic 3-phenyl-5-methyl-2H, 5H-furan-2-ones related to a natural product,(−)
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …

5-Acetoxymethyl-3-(4-bromophenyl)-2, 5-dihydrofuran-2-one previously described as highly
antifungally active was found to provide the corresponding 5-methylene derivative via an …

A small library of twenty-four quinoline based butenolides also known as furanones and
their nitrogen analogues was prepared by using two different aroylpropionic acids, viz. 3-(2 …

Pentenolide analogues of antifungal 3, 5-disubstituted butenolides were prepared by
oxidative cyclization of 2-(substituted aryl) hex-5-enoic acids as the key step. Given the …

Three new γ-hydroxyl butenolides (1–3), a pair of new enantiomeric spiro-butenolides (4a
and 4b), a pair of enantiomeric cyclopentenones (5a new and 5b new natural), and six …

This review surveys the literature published on the emerging biological properties of
furanodienone. Furanodienone (FDN)(1) is a furanosesquiterpenoid belonging to the class …

Herein, a divergent synthesis of a variety of 2α‐and 5α‐substituted furan derivatives from 2‐
hydroxy‐1, 4‐diones is reported. By using appropriate substrates and an acid catalyst, the …

A convenient route to new 3 (2H)-furanones is described through hydrogenolysis and
subsequent acidic hydrolysis of isoxazoles. The antiproliferative activity of title compounds …

The synthesis of fully substituted γ-hydroxybutenolides is possible by a Knoevenagel-type
ring condensation of α-methyleneketones and α-ketoesters under basic conditions. This …