Protein crowding in lipid bilayers gives rise to non-Gaussian anomalous lateral diffusion of phospholipids and proteins
Biomembranes are exceptionally crowded with proteins with typical protein-to-lipid ratios
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …
Anomalous and normal diffusion of proteins and lipids in crowded lipid membranes
Lateral diffusion plays a crucial role in numerous processes that take place in cell
membranes, yet it is quite poorly understood in native membranes characterized by, eg …
membranes, yet it is quite poorly understood in native membranes characterized by, eg …
[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …
connection to the binding of various particles and macromolecules to the membrane—are …
Reduced lateral mobility of lipids and proteins in crowded membranes
JE Goose, MSP Sansom - PLoS computational biology, 2013 - journals.plos.org
Coarse-grained molecular dynamics simulations of the E. coli outer membrane proteins
FhuA, LamB, NanC, OmpA and OmpF in a POPE/POPG (3∶ 1) bilayer were performed to …
FhuA, LamB, NanC, OmpA and OmpF in a POPE/POPG (3∶ 1) bilayer were performed to …
Diffusion of integral membrane proteins in protein-rich membranes
M Javanainen, H Martinez-Seara… - The journal of …, 2017 - ACS Publications
The lateral diffusion of embedded proteins along lipid membranes in protein-poor conditions
has been successfully described in terms of the Saffman–Delbrück (SD) model, which …
has been successfully described in terms of the Saffman–Delbrück (SD) model, which …
Development of anomalous diffusion among crowding proteins
In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous
landscape, where aggregates and dense domains of proteins or lipids obstruct the path of …
landscape, where aggregates and dense domains of proteins or lipids obstruct the path of …
[HTML][HTML] Effects of protein crowding on membrane systems
G Guigas, M Weiss - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Cellular membranes are typically decorated with a plethora of embedded and adsorbed
macromolecules, eg proteins, that participate in numerous vital processes. With typical …
macromolecules, eg proteins, that participate in numerous vital processes. With typical …
Anomalous diffusion of phospholipids and cholesterols in a lipid bilayer and its origins
Combining extensive molecular dynamics simulations of lipid bilayer systems of varying
chemical compositions with single-trajectory analyses, we systematically elucidate the …
chemical compositions with single-trajectory analyses, we systematically elucidate the …
Mechanisms underlying anomalous diffusion in the plasma membrane
D Krapf - Current topics in membranes, 2015 - Elsevier
The plasma membrane is a complex fluid where lipids and proteins undergo diffusive motion
critical to biochemical reactions. Through quantitative imaging analyses such as single …
critical to biochemical reactions. Through quantitative imaging analyses such as single …
Concerted diffusion of lipids in raft-like membranes
T Apajalahti, P Niemelä, PN Govindan… - Faraday …, 2010 - pubs.rsc.org
Currently, there is no comprehensive model for the dynamics of cellular membranes. The
understanding of even the basic dynamic processes, such as lateral diffusion of lipids, is still …
understanding of even the basic dynamic processes, such as lateral diffusion of lipids, is still …