CD81, the scavenger receptor‐BI (SR‐BI) and the low‐density lipoprotein receptor (LDLR)
are involved in peripheral blood mononuclear cells (PBMCs) hepatitis C virus (HCV) entry …

Objectives CD100, also known as Sema4D, is a member of the semaphorin family and has
important regulatory functions that promote immune cell activation and responses. The role …

The hepatitis C virus (HCV) envelope (E) 2 protein interacts with the cellular receptor CD81
leading to modulation of B and T cell function. Recently, a higher binding affinity of subtype …

Hepatitis C virus (HCV) causes chronic infection accompanied by a high risk of liver failure
and hepatocellular carcinoma. CD8+ T cell responses are important in the control of viremia …

Several cell surface molecules have hepatitis C virus (HCV) binding properties and may
serve as receptors facilitating viral entry into cells. The large extracellular loop (LEL) of …

: Background and Aims: Hepatitis C virus (HCV) entry, as the first key step during virus
infection, includes cell attachment, interactions of virus envelope proteins with receptors or …

Costimulatory signals via B7/CD28 family molecules (signal 2) are critical for effective
adaptive CD8+ T cell immune responses. In addition to costimulatory signals, B7/CD28 …

We investigated the responses of peripheral blood mononuclear cells (PBMCs) to hepatitis
C virus core protein in ten patients with chronic hepatitis C during interferon (IFN)-β …

To investigate whether therapy with alpha interferon (IFN-α) induces changes in intrahepatic
antigen-presenting cells (APCs), we obtained liver biopsy specimens before, during, and …

Aim: The aim of the present study is to study the mechanism of entry of hepatitis C virus
(HCV) into human cells. We examined the in vitro binding of HCV to various human cell lines …