Although chronic hepatitis C patients have a lower frequency and functions of dendritic cells
(DCs) than healthy subjects, little is known about the serial changes in frequency and …

Multiple interferon‐stimulated genes (ISGs) involving T‐cell activation are upregulated
during initial interferon‐α‐based therapy for chronic hepatitis C virus (HCV) infection …

Recent data highlighted the association of the macrophage activation marker CD 163 with
histological inflammation and fibrosis in chronic hepatitis C virus (HCV) infection. The aim of …

Dendritic cells (DC) are crucially involved in the induction of immune responses; however,
reports on DC functions in chronic hepatitis C are controversial. Function of DC includes …

BACKGROUND & AIMS: Virus-specific CD4+ T cells play a major role in hepatitis C virus
(HCV) infection. Viral clearance is associated with vigorous and multispecific CD4+ T cell …

It was estimated that up to 70% of hepatitis C virus (HCV)-infected subjects became
chronically infected, and these patients have an increased risk of developing cirrhosis and …

The functional impairment of HCV‐specific T cell responses is believed to be an important
determinant of HCV persistence, but the functional T cell defects of patients with chronic …

Background and Aims Hepatitis C virus (HCV) infection is a challenge to prevent and treat
because of the rapid development of drug resistance and escape. Viral entry is required for …

CD40, a member of the tumor necrosis factor receptor family, and its ligand, CD40L
(CD154), are important regulators of the antiviral immune response. CD40L is up‐regulated …

An estimated number of 71 million people are living with chronic hepatitis C virus (HCV)
infection worldwide and 400,000 annual deaths are related to the infection. HCV entry into …