The high levels of interleukin 10 (IL‐10) present in chronic hepatitis C virus (HCV) infection
have been suggested as responsible for the poor antiviral cellular immune responses found …

Defective T‐cell functions play a role in the persistence of HCV infection. Activated T cells
express CD137, which costimulates antivirus T‐cell responses, and this activity is …

A liver tissue recruitment of antigen-specific cytotoxic cells has been reported in chronic
hepatitis C virus (HCV) infection, but whether they really play a role in viral clearance is still …

BACKGROUND Upregulation of Th1 associated intrahepatic cytokines in chronic hepatitis C
virus (HCV) infection should lead to a significant non-specific cellular immune response, a …

Hepatitis C virus (HCV) infection represents a serious public health problem worldwide.
Development of new therapeutics against HCV has been hampered by the lack of a small …

Hepatitis C virus (HCV) causes a chronic liver infection, which may result in cirrhosis and
hepatocellular carcinoma. Impairment of the maturation process in dendritic cells (DCs) may …

All PCR products showed a single band at approximately 900 bp on ethidium bromide-
stained gels. Sequencing of PCR products showed a nucleotide substitution C596= T in one …

There is evidence that both cellular and humoral components of the immune response are
required for viral clearance to occur in chronic hepatitis B. Recent studies demonstrated that …

ABSTRACT The human CD81 (hCD81), the most recently proposed receptor of hepatitis C
virus (HCV), can especifically bind to HCV envelope glycoprotein 2 (E2). In this study …

Objective The aim of this study was to assess CD95 expression on peripheral blood
lymphocytes in patients with chronic hepatitis C virus (HCV) infection, both under interferon …