Immunological markers predicting outcome in patients with hepatitis C treated with interferon‐α and ribavirin

S Lee, GC MacQuillan, NM Keane… - Immunology and cell …, 2002 - Wiley Online Library
Type 1 (T1) cytokine responses are required for the clearance of hepatitis C virus by
cytotoxic T lymphocytes, but can promote liver damage. Interferon‐α (IFNα) can be expected …

[HTML][HTML] CD81 and hepatitis C virus (HCV) infection

L Fénéant, S Levy, L Cocquerel - Viruses, 2014 - mdpi.com
Hepatitis C Virus (HCV) infection is a global public health problem affecting over 160 million
individuals worldwide. Its symptoms include chronic hepatitis, liver cirrhosis and …

Cross-linking of CD81 by HCV-E2 protein inhibits human intrahepatic plasmacytoid dendritic cells response to CpG-ODN

Z Tu, P Zhang, H Li, J Niu, X Jin, L Su - Cellular immunology, 2013 - Elsevier
Plasmacytoid dendritic cells (pDCs) are reported to be defective in HCV-infected patients,
the mechanisms of which remain poorly understood. We isolated liver derived mononuclear …

Ribavirin increases mitogen- and antigen-induced expression of CD40L on CD4+ T cells in vivo

A Bergamini, M Cepparulo, F Bolacchi… - Clinical & …, 2002 - academic.oup.com
Here, CD40L expression and cytokine production have been analysed in peripheral blood
cells from orthotopic liver transplantation (OLT) recipients treated with ribavirin for recurrent …

CD81 large extracellular loop-containing fusion proteins with a dominant negative effect on HCV cell spread and replication

B Grigorov, J Molle, E Rubinstein… - Journal of General …, 2017 - microbiologyresearch.org
The roles of CD81 in the hepatitis C virus (HCV) life cycle are multiple but remain ill
characterized. CD81 is known to interact with the HCV glycoproteins as an attachment …

A prospective study of T‐ and B‐lymphocyte subpopulations, CD81 expression levels on B cells and regulatory CD4+CD25+CD127low/−FoxP3+ T cells in patients …

B Soldevila, N Alonso… - Journal of viral …, 2011 - Wiley Online Library
Resolution of hepatitis C virus (HCV) infection requires a complex interplay between innate
and adaptative immune responses. The role of lymphocyte subpopulations during combined …

Interleukin-7 augments CD8+ T cells function and promotes viral clearance in chronic hepatitis C virus infection

H Hou, Y Kang, Y Zeng, Y Li, J Shang - Cytokine, 2018 - Elsevier
Abstract Interleukin (IL)-7 is a potent proliferation, activation, and survival cytokine for CD8+
T cells to improve viral and tumor specific CD8+ T cell responses. However, the role of IL-7 …

CD44 participates in IP-10 induction in cells in which hepatitis C virus RNA is replicating, through an interaction with Toll-like receptor 2 and hyaluronan

T Abe, T Fukuhara, X Wen, A Ninomiya… - Journal of …, 2012 - Am Soc Microbiol
The mechanisms of induction of liver injury during chronic infection with hepatitis C virus
(HCV) are not well understood. Gamma interferon (IFN-γ)-inducible protein 10 (IP-10), a …

[HTML][HTML] Lymphocyte CD64 increased in patients with chronic HBV infection

H Feng, J Yin, YP Han, XY Zhou… - International Journal of …, 2015 - ncbi.nlm.nih.gov
CD64 was up-regulated in infection diseases, but there was no report about the change of
CD64 in chronic hepatitis B virus (HBV) infection. The purpose of this study was to determine …

Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles

B Mazumdar, H Kim, K Meyer, SK Bose… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT CD55 limits excessive complement activation on the host cell surface by
accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus …