The genomic relationship matrix plays a key role in the analysis of genetic diversity, genomic
prediction, and genome-wide association studies. The epistatic genomic relationship matrix …

Whole genome epistasis models with interactions between different loci can be
approximated by genomic relationship models based on Hadamard powers of the additive …

Key message Models based on additive marker effects and on epistatic interactions can be
translated into genomic relationship models. This equivalence allows to perform predictions …

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The application of genetic relationships among individuals, characterized by a genetic
relationship matrix (GRM), has far-reaching effects in human genetics. However, the current …

Background In recent theoretical developments, the information available (eg genotypes)
divides the original population into two groups: animals with this information (selected …

Motivation The resemble between relatives computed from pedigree and genomic data is an
important resource for geneticists and ecologists, who are interested in understanding how …

Large-scale, multilocus genetic association studies require powerful and appropriate
statistical-analysis tools that are designed to relate genotype and haplotype information to …

Epistasis is a ubiquitous phenomenon in genetics, and is considered to be one of the main
factors in current efforts to detect missing heritability for complex diseases. Simulation is a …

Haplotype prediction models open many possibilities to improve the accuracy of genomic
selection but require more data processing and computing time than single-SNP prediction …