Erectile dysfunction resulting from pelvic surgery is associated with changes in cavernosal gene expression indicative of cavernous nerve injury
G Villegas, MT Tar, KP Davies - Andrologia, 2022 - Wiley Online Library
Pelvic surgery, even without direct cavernous nerve injury, carries a high risk of post‐
operative erectile dysfunction. The present studies were aimed at identifying molecular …
operative erectile dysfunction. The present studies were aimed at identifying molecular …
A mouse model of cavernous nerve injury-induced erectile dysfunction: functional and morphological characterization of the corpus cavernosum
HR Jin, YG Chung, WJ Kim, LW Zhang… - The Journal of …, 2010 - academic.oup.com
Introduction With the advent of genetically engineered mice, it seems important to develop a
mouse model of cavernous nerve injury (CNI). Aim To establish a mouse model of CNI …
mouse model of cavernous nerve injury (CNI). Aim To establish a mouse model of CNI …
M1 macrophages are predominantly recruited to the major pelvic ganglion of the rat following cavernous nerve injury
Introduction Neurogenic erectile dysfunction is a common sequela of radical prostatectomy.
The etiology involves injury to the autonomic cavernous nerves, which arise from the major …
The etiology involves injury to the autonomic cavernous nerves, which arise from the major …
[HTML][HTML] Gene expression profile comparison in the penile tissue of diabetes and cavernous nerve injury-induced erectile dysfunction rat model
Purpose To investigate the effects of cavernous nerve injury (CNI) on gene expression
profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to …
profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to …
Increased level of tumor necrosis factor-alpha (TNF-α) leads to downregulation of nitrergic neurons following bilateral cavernous nerve injury and modulates penile …
H Matsui, NA Sopko, JD Campbell, X Liu… - The journal of sexual …, 2021 - academic.oup.com
Background Erectile dysfunction (ED) after injury to peripheral cavernous nerve (CN) is
partly a result of inflammation in pelvic ganglia, suggesting that ED may be prevented by …
partly a result of inflammation in pelvic ganglia, suggesting that ED may be prevented by …
Whole genome microarray of the major pelvic ganglion after cavernous nerve injury: new insights into molecular profile changes after nerve injury
G Calenda, TD Strong, CP Pavlovich… - BJU …, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? With the present study, we
aimed to provide a global picture of the molecular processes that are activated by CN injury …
aimed to provide a global picture of the molecular processes that are activated by CN injury …
The development of a rat model of erectile dysfunction after radical prostatectomy: preliminary findings
O Kaufmann, J Claro, J Cury, E Andrade… - BJU …, 2008 - Wiley Online Library
OBJECTIVE To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury.
MATERIALS AND METHODS Given the great similarity between the anatomical structure of …
MATERIALS AND METHODS Given the great similarity between the anatomical structure of …
Cavernous nerve injury using rodent animal models
O Canguven, A Burnett - The journal of sexual medicine, 2008 - academic.oup.com
Introduction With the advance of the “nerve sparing” technique in radical pelvic surgeries,
medically unaided rates of normal erectile function following surgery have improved. Precise …
medically unaided rates of normal erectile function following surgery have improved. Precise …
Pathway analysis of microarray data from corpora cavernosal tissue of patients with a prostatectomy or Peyronie disease in comparison with a cavernous nerve …
T Searl, S Ohlander, KT McVary… - The journal of sexual …, 2023 - academic.oup.com
Introduction Patients with a prostatectomy are at high risk of developing erectile dysfunction
(ED) that is refractory to phosphodiesterase type 5 inhibitors. The cavernous nerve (CN) is …
(ED) that is refractory to phosphodiesterase type 5 inhibitors. The cavernous nerve (CN) is …
Increased expression of nestin in the major pelvic ganglion following cavernous nerve injury
In an effort to identify neuronal repair mechanisms of the major pelvic ganglion (MPG), we
evaluated changes in the expression of nestin, an intermediate filament protein and neural …
evaluated changes in the expression of nestin, an intermediate filament protein and neural …
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