Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …

The current spread of multi-drug resistance in a number of key pathogens and the lack of
therapeutic solutions in development to address most of the emerging infections in the clinic …

Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

The soil actinomycetes have been important sources of antibiotics, but were nearly
abandoned in recent years in favor of high-throughput target-based screening of chemical …

Actinomycetes are prolific sources of bioactive molecules. Traditional workflows including
bacterial isolation, fermentation, metabolite identification and structure elucidation have …

Microbial natural products, in particular, the ones produced by the members of the order
Actinomycetales, will continue to represent an important route to the discovery of novel …

Covering: up to February 2019 Actinomycetes are Gram positive bacteria of the phylum
Actinobacteria. These organisms are one of the most important sources of structurally …

Background Antibiotic resistance is on the rise, and new antibiotic research has slowed in
recent years, necessitating the discovery of possibly novel microbial resources capable of …

Covering: up to mid-2009 The phylum Actinobacteria hosts diverse high G+ C, Gram-
positive bacteria that have evolved a complex chemical language of natural product …

The prevalence of antimicrobial-resistant pathogens has highlighted the urgent need for
new drugs. Actinomycetes have been the most prominent sources of natural products for …