The incidence of end-stage renal disease attributable to hypertension is 5-fold greater in
African Americans than in whites. To determine whether glomerular hyperfiltration is an …

Previous studies have suggested striking racial differences in hypertension-related renal
disease. To explore potential mechanisms responsible for these differences, we investigated …

Renal perfusion and function in healthy African Americans. Background Despite their
increased risk of nephropathy, remarkably little is known about renal perfusion and function …

We analyzed the clinical courses of 94 patients with treated primary hypertension and
initially normal serum creatinine concentrations (≤ 133 μmol per liter [≤ 1.5 mg per …

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The African-American Study of Kidney Disease and Hypertension pilot study randomized 94
nondiabetic black men and women (mean age, 53 years; 75% male) with presumed …

Renal function measurements were obtained in 1,703 African Americans with presumed
hypertensive nephrosclerosis who were screened for entry into the African-American Study …

Clinical and epidemiologic data support the contention that black people have a higher
incidence and severity of essential hypertension than white people, a phenomenon which is …

African-Americans with essential hypertension are more prone to the development of renal
failure and are frequently salt-sensitive as well. Because alterations of intrarenal …

African Americans have a disproportionate burden of chronic kidney disease (CKD), which
tends to have an earlier onset and a more rapid progression in this population. Many of the …