We recorded from single neurons in the hippocampus and entorhinal cortex (EC) of rats to
investigate the role of these structures in navigation and memory representation. Our results …

INTRODUCTION Place cells are neurons in the hippocampus that represent the animal's
position in space and are important for supporting navigation behaviors. These cells …

We explore the environment not only by navigating, but also by viewing our surroundings
with our eyes. Here we review growing evidence that the mammalian hippocampal …

The neural basis of navigation by humans was investigated with functional neuroimaging of
brain activity during navigation in a familiar, yet complex virtual reality town. Activation of the …

Spatial navigation and memory are often seen as heavily intertwined at the cognitive and
neural levels of analysis. We review models that hypothesize a central role for the medial …

The ability to orientate within familiar environments relies on the formation and use of a
mental representation of the environment, namely a cognitive map. Neuropsychological and …

The navigational system of the mammalian cortex comprises a number of interacting brain
regions. Grid cells in the medial entorhinal cortex and place cells in the hippocampus are …

Decades of research have established the importance of the hippocampus for episodic and
spatial memory. In spatial navigation tasks, the role of the hippocampus has been classically …

Memory research remains focused on just a few brain structures–in particular, the
hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries …

▪ Abstract The startling discovery by O'Keefe & Dostrovsky (Brain Res.; 34: 171–75) that
hippocampal neurons fire selectively in different regions or “place fields” of an environment …