Challenges and strategies: scalable and efficient production of mesenchymal stem cells-derived exosomes for cell-free therapy

W Pan, H Chen, A Wang, F Wang, X Zhang - Life sciences, 2023 - Elsevier
Exosomes are small membrane vesicles secreted by most cell types, and widely exist in cell
supernatants and various body fluids. They can transmit numerous bioactive elements, such …

New therapeutic approaches of mesenchymal stem cells-derived exosomes

J Janockova, L Slovinska, D Harvanova… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the
treatment of several diseases due to their differentiation and immunomodulatory capabilities …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine

ZJ Ma, JJ Yang, YB Lu, ZY Liu… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent stem cells with marked potential for
regenerative medicine because of their strong immunosuppressive and regenerative …

Techniques for increasing the yield of stem cell-derived exosomes: what factors may be involved?

ZY Feng, QY Zhang, J Tan, HQ Xie - Science China Life sciences, 2022 - Springer
Exosomes are nano-scale extracellular vesicles secreted by cells and constitute an
important part in the cell-cell communication. The main contents of the exosomes include …

Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials

A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …

Advances in mesenchymal stem cell exosomes: a review

Y Tang, Y Zhou, HJ Li - Stem cell research & therapy, 2021 - Springer
Stem cells can be used for regenerative medicine and as treatments for disease. The
application of tissue engineering-related transplantation, stem cells, and local changes in …

Advances in mesenchymal stem cell-derived exosomes as drug delivery vehicles

D Rao, D Huang, C Sang, T Zhong, Z Zhang… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes are tiny vesicles with a double membrane structure that cells produce. They
range in diameter from 40 to 150 nm and may contain a variety of biomolecules including …

Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes

BC Lee, I Kang, KR Yu - Journal of clinical medicine, 2021 - mdpi.com
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …

Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

[HTML][HTML] Current understanding of the mesenchymal stem cell-derived exosomes in cancer and aging

M Muralikumar, SM Jain, H Ganesan, AK Duttaroy… - Biotechnology …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are being widely researched upon for several years with
translational application in regenerative medicine. Many studies acknowledged trophic …