Purpose Pharmacy department contributions to a medical center's broad initiative to improve
sepsis care outcomes are described. Summary Timely and appropriate antimicrobial therapy …

Background: Sepsis and septic shock remain a significant burden on the US health care
system. A multidisciplinary response system (Coordinated Response to Sepsis, CaRTS) that …

Purpose A review of the impact of pharmacists on appropriate medication selection, timing of
administration, and as members of a multidisciplinary sepsis response team. Summary Early …

Sepsis mortality may be improved by early recognition and appropriate treatment based on
evidence-based guidelines. An intervention was developed that focused on earlier …

Background: Studies evaluating the clinical effectiveness of sepsis screening tools and
methods to improve the time from diagnosis to antibiotic administration are needed to …

Introduction Sepsis is a life‐threatening medical emergency and a leading cause of
morbidity and mortality worldwide. Reductions in time to antibiotics in patients presenting …

Background: Current guidelines for septic shock management recommend administration of
appropriate, broad-spectrum antimicrobials within 1 hour of recognition. Objective: To …

Background Current evidence suggests that administration of appropriate antibiotic therapy
within 1 h after the onset of hypotension significantly improves mortality rates among …

OBJECTIVES: Results of pre-post intervention studies of sepsis early warning systems have
been mixed, and randomized clinical trials showing efficacy in the emergency department …

Background Guidelines recommend initiation of appropriate antimicrobial therapy within 1 h
of severe sepsis diagnosis. Few sepsis bundles exist in the literature emphasizing initiation …